Evidence map›Paper›PMID 38414122›Full record

ArticleAnnals of coloproctology2024

Long-term clinical outcomes after high and low ligations with lymph node dissection around the root of the inferior mesenteric artery in patients with rectal cancer.

Min Wan Lee, Sung Sil Park, Kiho You, Dong Eun Lee, Dong Woon Lee, Sung Chan Park, Kyung Su Han, Dae Kyung Sohn, Chang Won Hong, Bun Kim and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Min Wan LeeCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Sung Sil ParkCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Kiho YouCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Dong Eun LeeBiostatistics Collaboration Team, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Dong Woon LeeCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Sung Chan ParkCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Kyung Su HanCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Dae Kyung SohnCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Chang Won HongCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Bun KimCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Byung Chang KimCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Hee Jin ChangCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Dae Yong KimCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Jae Hwan OhCenter for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
National Cancer Center · KR

Funding

National Cancer Center 2110201-3
6 · The paper itself

Abstract

purposeThis study aimed to evaluate the long-term clinical outcomes based on the ligation level of the inferior mesenteric artery (IMA) in patients with rectal cancer.

methodsThis was a retrospective analysis of a prospectively collected database that included all patients who underwent elective low anterior resection for rectal cancer between January 2013 and December 2019. The clinical outcomes included oncological outcomes, postoperative complications, and functional outcomes. The oncological outcomes included overall survival (OS) and relapse-free survival (RFS). The functional outcomes, including defecatory and urogenital functions, were analyzed using the Fecal Incontinence Severity Index, International Prostate Symptom Score, and International Index of Erectile Function questionnaires.

resultsIn total, 545 patients were included in the analysis. Of these, 244 patients underwent high ligation (HL), whereas 301 underwent low ligation (LL). The tumor size was larger in the HL group than in the LL group. The number of harvested lymph nodes (LNs) was higher in the HL group than in the LL group. There were no significant differences in complication rates and recurrence patterns between the groups. There were no significant differences in 5-year RFS and OS between the groups. Cox regression analysis revealed that the ligation level (HL vs. LL) was not a significant risk factor for oncological outcomes. Regarding functional outcomes, the LL group showed a significant recovery in defecatory function 1 year postoperatively compared with the HL group.

conclusionLL with LNs dissection around the root of the IMA might not affect the oncologic outcomes comparing to HL; however, it has minimal benefit for defecatory function.

Indexed as

Anastomotic leakageFunctional outcomesInferior mesenteric arteryRectal neoplasmsSurvival

Identifiers

PMID38414122
PMCPMC10915527
OpenAlexW4392148681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.