Evidence map›Paper›PMID 38414038›Full record

ArticleBMC biology2024

Membranes are functionalized by a proteolipid code.

Troy A Kervin, Michael Overduin

Open access · goldAbstract read
In one paragraph

Article in BMC biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Protein-enhanced small molecule disruptors of ordered membrane domains.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Hydrophobic mismatch induces lipid sorting based on tail unsaturation.bioRxiv : the preprint server for biology · 2026
    Article
  4. Deciphering the language of mingling lipids and proteins.Current opinion in structural biology · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Troy A KervinDivision of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. troy.kervin@magd.ox.ac.uk.ORCID https://orcid.org/0000-0002-7681-6861
Michael OverduinDepartment of Biochemistry, University of Alberta, Edmonton, AB, Canada. overduin@ualberta.ca.ORCID http://orcid.org/0000-0002-3114-6585
Centre for Human Genetics · GBUniversity of Alberta · CA

Funding

NSERC RGPIN- 2018- 04994
6 · The paper itself

Abstract

Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins.

Indexed as

Carrier ProteinsProteolipidsCell MembraneMembranesCarrier ProteinsProteolipidsFingerprintIntegral membrane proteinLipidonPeripheral membrane proteinPhosphoinositideProtein islandProteolipid codeZoneZoning

Identifiers

PMID38414038
PMCPMC10898092
OpenAlexW4392192276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.