Evidence map›Paper›PMID 38414035›Full record

ArticleAlzheimer's research & therapy2024

Machine learning prediction of future amyloid beta positivity in amyloid-negative individuals.

Elaheh Moradi, Mithilesh Prakash, Anette Hall, Alina Solomon, Bryan Strange, Jussi Tohka, Alzheimer’s Disease Neuroimaging Initiative

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Predicting Future Brain Atrophy Based on Longitudinal MRI.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Elaheh MoradiA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, 70150, Finland. elaheh.moradi@uef.fi.
Mithilesh PrakashA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, 70150, Finland.
Anette HallInstitute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.
Alina SolomonInstitute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.
Bryan StrangeLaboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSC, Madrid, Spain.
Jussi TohkaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, 70150, Finland.
Alzheimer’s Disease Neuroimaging Initiative
University of Eastern Finland · FIImperial College London · GBUniversidad Politécnica de Madrid · ES

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
European Research CouncilNIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

backgroundThe pathophysiology of Alzheimer's disease (AD) involves

methodsWe propose a machine learning framework using standard non-invasive (MRI, demographics, APOE, neuropsychology) measures to predict future A

resultsCross-validated AUC for 4-year A

conclusionStandard measures have potential in detecting future A

Indexed as

Alzheimer DiseaseCognitive DysfunctionAmyloid beta-PeptidesBiomarkersHumansMachine LearningPositron-Emission Tomographytau ProteinsAmyloid beta-PeptidesBiomarkerstau ProteinsAlzheimer’s diseaseAmyloid betaConversion predictionMachine learningMild cognitive impairment

Identifiers

PMID38414035
PMCPMC10900722
OpenAlexW4392200056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.