Evidence map›Paper›PMID 38414028›Full record

ArticleVirology journal2024

Molecular epidemiology and phylogenetic analysis of feline calicivirus in Kunshan, China.

Semin Kim, Yixi Cheng, Zhenkun Fang, Xinyue Liu, Qiu Zhongqi, Yu Weidong, Aysun Yilmaz, Huseyin Yilmaz, Sajid Umar

Open access · goldAbstract read
In one paragraph

Article in Virology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  3. Isolation, Identification, and Genetic Evolution Analysis ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Semin KimGlobal Health Research Center (GHRC), Duke Kunshan University, Suzhou, China.
Yixi ChengGlobal Health Research Center (GHRC), Duke Kunshan University, Suzhou, China.
Zhenkun FangGlobal Health Research Center (GHRC), Duke Kunshan University, Suzhou, China.
Xinyue LiuGlobal Health Research Center (GHRC), Duke Kunshan University, Suzhou, China.
Qiu ZhongqiSimba Pet Hospital, Tinglin Park Branch), Maanshan Road, 215335, Kunshan, Suzhou, Jiangsu Province, China.
Yu WeidongPlay Pi Kangkang Pet Hospital, Kunshan City Development Zone, 215300, Kunshan, Suzhou, Jiangsu Province, China.
Aysun YilmazDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, 35500, Büyükcekmece, Istanbul, Turkey.
Huseyin YilmazDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, 35500, Büyükcekmece, Istanbul, Turkey.
Sajid UmarGlobal Health Research Center (GHRC), Duke Kunshan University, Suzhou, China. sajid.umar@dukekunshan.edu.cn.ORCID 0000-0001-7646-4125
Duke Kunshan University · CNIstanbul University-Cerrahpaşa · TR

Funding

Duke Kunshan University and Kunshan Municipal Government research funding. 202216406005Z-22KKSGR075
6 · The paper itself

Abstract

Feline calicivirus (FCV) is a highly contagious virus in cats, which typically causes respiratory tract and oral infections. Despite vaccination against FCV being a regular practice in China, new FCV cases still occur. Antigenic diversity of FCV hinders the effective control by vaccination. This is first report which aims to investigate the molecular epidemiology and molecular characteristics of FCV in Kunshan, China. The nasopharyngeal swabs were collected from cats showing variable clinical signs from different animal clinics in Kunshan from 2022 to 2023. Preliminary detection and sequencing of the FCV capsid gene were performed to study genetic diversity and evolutionary characteristics. FCV-RNA was identified in 52 (26%) of the samples using RT-PCR. A significant association was found between FCV-positive detection rate, age, gender, vaccination status and living environment, while a non-significant association was found with breed of cats. Nucleotide analysis revealed two genotypes, GI and GII. GII predominated in Kunshan, with diverse strains and amino acid variations potentially affecting vaccination efficacy and FCV detection. Notably, analysis pinpointed certain strains' association with FCV-virulent systemic disease pathotypes. This investigation sheds light on FCV dynamics, which may aid in developing better prevention strategies and future vaccine designs against circulating FCV genotypes.

Indexed as

Caliciviridae InfectionsCalicivirus, FelineCat DiseasesAnimalsCapsid ProteinsCatsMolecular EpidemiologyPhylogenyRNACapsid ProteinsRNACatsChinaEpidemiologyFeline calicivirusGenetic diversityPhylogenetic Analysis

Identifiers

PMID38414028
PMCPMC10900597
OpenAlexW4392198877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.