Evidence map›Paper›PMID 38413997›Full record

Trial reportInternational breastfeeding journal2024

Prelacteal feeding is not associated with infant size at 3 months in rural Bangladesh: a prospective cohort study.

Hannah Tong, Andrew Thorne-Lyman, Amanda C Palmer, Saijuddin Shaikh, Hasmot Ali, Ya Gao, Monica M Pasqualino, Lee Wu, Kelsey Alland, Kerry Schulze and 3 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International breastfeeding journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02909179 nacompletednot on this map

mCARE II: Enhancing, Integrating and Scaling mCARE and Measuring the Impact of a Mobile Health System to Support Healthy Pregnancies and Improve Newborn Survival

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2016 to 2020Enrolled113,539ConditionsHigh Perinatal Mortality, High Neonatal Mortality, Low Antenatal Care Service Utilization, Low Postnatal Care Service UtilizationArmsmCARE-II
NCT03683667 phase2 / phase3completednot on this map

Efficacy of Supplemental Protein, Delivered Alone or in Combination With Treatment for Enteric Pathogens, to Prevent Growth Faltering in Bangladeshi Infants

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2018 to 2020Enrolled5,283ConditionsStunting, Malnutrition, Protein, Enteric PathogensArmsAzithromycin Oral Product, Placebos, Protein Supplement, Isocaloric Supplement, Egg
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Effect of infant feeding practices on stunting and wasting in Northwest Ethiopia: a birth cohort study.Archives of public health = Archives belges de sante publique · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hannah TongDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Andrew Thorne-LymanDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Amanda C PalmerDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. acpalmer@jhu.edu.
Saijuddin ShaikhJiVitA Project, Johns Hopkins University, Bangladesh (JHU,B) Keranipara, Rangpur, Bangladesh.
Hasmot AliJiVitA Project, Johns Hopkins University, Bangladesh (JHU,B) Keranipara, Rangpur, Bangladesh.
Ya GaoDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Monica M PasqualinoDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Lee WuDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kelsey AllandDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kerry SchulzeDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Keith P WestDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Md Iqbal HossainInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Alain B LabriqueDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly and exclusive breastfeeding may reduce neonatal and post-neonatal mortality in low-resource settings. However, prelacteal feeding (PLF), the practice of giving food or liquid before breastfeeding is established, is still a barrier to optimal breastfeeding practices in many South Asian countries. We used a prospective cohort study to assess the association between feeding non-breastmilk food or liquid in the first three days of life and infant size at 3-5 months of age.

methodsThe analysis used data from 3,332 mother-infant pairs enrolled in a randomized controlled trial in northwestern rural Bangladesh conducted from 2018 to 2019. Trained interviewers visited women in their households during pregnancy to collect sociodemographic data. Project staff were notified of a birth by telephone and interviewers visited the home within approximately three days and three months post-partum. At each visit, interviewers collected data on breastfeeding practices and anthropometric measures. Infant length and weight measurements were used to produce length-for-age (LAZ), weight-for-age (WAZ), and weight-for-length (WLZ) Z-scores. We used multiple linear regression to assess the association between anthropometric indices and PLF practices, controlling for household wealth, maternal age, weight, education, occupation, and infant age, sex, and neonatal sizes.

resultsThe prevalence of PLF was 23%. Compared to infants who did not receive PLF, infants who received PLF may have a higher LAZ (Mean difference (MD) = 0.02 [95% CI: -0.04, 0.08]) score, a lower WLZ (MD=-0.06 [95% CI: -0.15, 0.03]) score, and a lower WAZ (MD=-0.02 [95% CI: -0.08, 0.05]) score at 3-5 months of age, but none of the differences were statistically significant. In the adjusted model, female sex, larger size during the neonatal period, higher maternal education, and wealthier households were associated with larger infant size.

conclusionPLF was a common practice in this setting. Although no association between PLF and infant growth was identified, we cannot ignore the potential harm posed by PLF. Future studies could assess infant size at an earlier time point, such as 1-month postpartum, or use longitudinal data to assess more subtle differences in growth trajectories with PLF.

trial registrationClinicalTrials.gov: NCT03683667 and NCT02909179.

Indexed as

Breast FeedingFeeding BehaviorBangladeshFemaleHumansInfantInfant, NewbornPregnancyProspective StudiesSocioeconomic FactorsBreastfeedingEarly newborn foodInfant developmentNeonatal healthPrelactealSouth Asia

Identifiers

PMID38413997
PMCPMC10900540

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.