Evidence map›Paper›PMID 38413972›Full record

ArticleHarm reduction journal2024

"They make it too hard and too many hoops to jump": system and organizational barriers to drug treatment during epidemic rates of opioid overdose.

Julia Dickson-Gomez, Sarah Krechel, Jessica Ohlrich, Helena Danielle Green Montaque, Margaret Weeks, Jianghong Li, Jennifer Havens, Antoinette Spector

Open access · goldAbstract read
In one paragraph

Article in Harm reduction journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. An antifentanyl monoclonal antibody reverses fentanyl-induced apnea in pigs.The Journal of pharmacology and experimental therapeutics · 2025
    Article
  4. Mining Social Media for Barriers to Opioid Recovery with LLMs.Proceedings of the ... Workshop on Patient-Oriented Language Processing · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Julia Dickson-GomezMedical College of Wisconsin, Milwaukee, USA. jdickson@mcw.edu.
Sarah KrechelMedical College of Wisconsin, Milwaukee, USA.
Jessica OhlrichMedical College of Wisconsin, Milwaukee, USA.
Helena Danielle Green MontaqueMedical College of Wisconsin, Milwaukee, USA.
Margaret WeeksMedical College of Wisconsin, Milwaukee, USA.
Jianghong LiMedical College of Wisconsin, Milwaukee, USA.
Jennifer HavensMedical College of Wisconsin, Milwaukee, USA.
Antoinette SpectorMedical College of Wisconsin, Milwaukee, USA.
Medical College of Wisconsin · US

Funding

Effects of State Laws to Reduce Opioid Diversion on Transitions to Injection Drug Use and HIV/HCV TransmissionR01DA044971 · NIDA · MEDICAL COLLEGE OF WISCONSIN · PI DICKSON-GOMEZ, JULIA B · 2018 to 2022
$3.0M
NIDA NIH HHS R01 DA044971
6 · The paper itself

Abstract

introductionThe United States is currently facing an opioid overdose crisis. Research suggests that multiple interventions are needed to reduce overdose deaths including increasing access and retention to medications to treat opioid use disorders (MOUD, i.e., methadone, buprenorphine, and naltrexone) and increasing the distribution and use of naloxone, a medication that can reverse the respiratory depression that occurs during opioid overdoses. However, barriers to MOUD initiation and retention persist and discontinuations of MOUD carry a heightened risk of overdose. Many times, MOUD is not sought as a first line of treatment by people with opioid use disorder (OUD), many of whom seek treatment from medically managed withdrawal (detox) programs. Among those who do initiate MOUD, retention is generally low. The present study examines the treatment experiences of people who use opioids in three states, Connecticut, Kentucky, and Wisconsin.

methodsWe conducted in-depth interviews with people who use opioids in a rural, urban, and suburban area of three states: Connecticut, Kentucky and Wisconsin. Data analysis was collaborative and key themes were identified through multiple readings, coding of transcripts and discussion with all research team members.

resultsResults reveal a number of systemic issues that reduce the likelihood that people initiate and are retained on MOUD including the ubiquity of detox as a first step in drug treatment, abstinence requirements and requiring patients to attend group treatment. MOUD-related stigma was a significant factor in the kinds of treatment participants chose and their experiences in treatment.

conclusionsInterventions to reduce MOUD stigma are needed to encourage MOUD as a first course of treatment. Eliminating abstinence-based rules for MOUD treatment may improve treatment retention and decrease overdose risk.

Indexed as

BuprenorphineDrug OverdoseEpidemicsOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidHumansOpiate Substitution TreatmentAnalgesics, OpioidBuprenorphineDetoxFentanylHeroinMedically assisted withdrawalMedications to treat opioid use disorder (MOUD)Opioid use disorderOverdosePolysubstance use

Identifiers

PMID38413972
PMCPMC10900746
OpenAlexW4392200295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.