ArticleHealth and quality of life outcomes2024
Associations of multimorbidity with body pain, sleep duration, and depression among middle-aged and older adults in China.
Article in Health and quality of life outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Multimorbidity and the risk of depression: a systematic review of cohort studies.Journal of global health · 2026Pooled it
- A transdisciplinary framework for chronic illness and chronic pain: a sequential qualitative meta-synthesis.Frontiers in public health · 2026Pooled it
- Longitudinal Patterns of Within- and Cross-Domain Multimorbidity Across Physical, Psychological, and Cognitive Conditions in China and the United States: The Role of Socioeconomic and Healthcare Inequalities.Healthcare (Basel, Switzerland) · 2026Article
- Dose-Related Associations Between Physical Activity and Multimorbidity Among Middle-Aged and Older Adults.Journal of prevention (2022) · 2026Article
- Urban-rural differences in depressive symptoms and related factors among employed middle-aged and older adults: a national cross-sectional study in China.BMC public health · 2026Article
- The association between disease status and health-related quality of life: evidence from a cross-sectional survey across mainland China.Health and quality of life outcomes · 2026Article
- [The Association Between Depressive Symptoms and Multimorbidity Among Middle-Aged and Older Adults in Rural China: Sequential Mediation Effects of Pain and Activities of Daily Living].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Prevalence and related influencing factors of depression symptoms among empty-nest elderly in China.Scientific reports · 2026Article
- Patterns of depressive symptoms among older adults living in long-term care homes in China: a latent class analysis.Frontiers in public health · 2026Article
- Chain mediating effect of somatic pain and sleep duration between chronic disease count and depressive symptoms in older adults.Frontiers in psychiatry · 2026Article
- Depression and Longitudinal Frailty Trajectories in Middle-Aged and Older Adults with Chronic Pain: A 8-Year National Cohort Study in China.Psychology research and behavior management · 2026Article
- Association between cognitive leisure activities and symptoms of depression in Chinese middle-aged and older adults: A CHARLS cohort study from 2011 to 2018.Global mental health (Cambridge, England) · 2026Article
- Lagged symptom-level associations among pain, sleep disturbance, and depressive-affective symptoms in adults aged ≥50 years: an international longitudinal multi-cohort study.Frontiers in medicine · 2026Article
- Social isolation to depression: the chain mediating effect of sleep duration and frailty-evidence from a Chinese nationwide cross-sectional study.BMC geriatrics · 2025Article
- Activating health behaviors: how does digital infrastructure improve the physical health of middle-aged and older adults? Evidence from the 'Broadband China' pilot policy.Global health action · 2025Article
- Prevalence, Geographic Variations, and Determinants of Pain Among Older Adults in China: Findings from the National Urban and Rural Elderly Population (UREP) Survey.Healthcare (Basel, Switzerland) · 2025Article
- Characterization and factors influencing the uncertainty of intolerable in older adults with multimorbidity: A Cross-sectional study.BMC geriatrics · 2025Article
- [Actor-Partner Interdependence Model Analysis of the Relationship Between Individual Social Capital and Depressive Symptoms Among Older Couples Across Different Socioeconomic Statuses].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Mediation of the frailty index, the relationship between sleep duration and chronic pain in different body regions: insights from the CHARLS cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- Who Benefits the Most from Sleep Hygiene Education? Findings from the SLeep Education for Everyone Program (SLEEP).Clocks & sleep · 2025Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
backgroundMultimorbidity, body pain, sleep disturbance, and depression are major clinical and public health challenges. This paper aimed to examine the associations of multimorbidity with body pain, sleep duration, and depression; and whether the associations varied by socioeconomic status.
methodsData was derived from four waves of the nationally representative China Health and Retirement Longitudinal Study (CHARLS), including participants aged 45 years and older in 2011. 12 physical non-communicable diseases and 1 mental chronic disease were used to measure multimorbidity. Educational attainment and annual per-capita household consumption expenditure were employed as proxies for socioeconomic status.
resultsOf the 16,931 participants aged 45 + years old, the proportion of people with multimorbidity was 37.87% at baseline. The number of multimorbidity increased with older age and higher socioeconomic status. Multimorbidity was associated with more body pain (incidence rate ratio (IRR) = 1.53, 95% CI = 1.45-1.61), and decreased sleep duration (β = -0.26, 95% CI = -0.36--0.15). Furthermore, multimorbidity was associated with increased depression risks (odds ratio (OR) = 1.54, 95% CI = 1.44-1.64, adjusted for sociodemographic variables), with the mediating effects of the number of body pain and sleep duration. The associations between multimorbidity and depression persisted among different socioeconomic groups.
conclusionsMultimorbidity was associated with increased body pain, decreased sleep duration, and further led to increased depression risks. It is necessary to pay attention to the multimorbidity of middle-aged and older adults, relieve their body pain, guarantee sufficient sleep, so as to reduce depression risks.
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