Evidence map›Paper›PMID 38413758›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

The impact of volume and neonatal level of care on outcomes of moderate and late preterm infants.

Elizabeth G Salazar, Molly Passarella, Brielle Formanowski, Ciaran S Phibbs, Scott A Lorch, Sara C Handley

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Local availability of neonatal intensive care at rural hospitals with childbirth services.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elizabeth G SalazarDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. salazare@chop.edu.ORCID 0000-0001-6998-5977
Molly PassarellaDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Brielle FormanowskiDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ciaran S PhibbsStanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-4353-3507
Scott A LorchDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Sara C HandleyDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-8436-4351
Children's Hospital of Philadelphia · USSalus University · USVA Palo Alto Health Care System · US

Funding

Training in Critical Care Health Policy ResearchT32HL098054 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Scott D Halpern · 2010 to 2026
$8.2M
Effect of Changing NICU Patient Volumes and Levels of Care on Neonatal OutcomesR01HD084819 · NICHD · STANFORD UNIVERSITY · PI LORCH, SCOTT A, PHIBBS, CIARAN S. · 2016 to 2018
$1.1M
The impact of delivery hospital organizational structure and culture on perinatal outcomesK23HD109426 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Sara Christine Handley · 2023 to 2026
$621k
HEAL Initiative: Antenatal Opioid Exposure Longitudinal Study ConsortiumUG1HD104252 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Sara Bonamo DeMauro, Scott A Lorch · 2024 to 2026
$425k
NHLBI NIH HHS T32 HL098054NICHD NIH HHS K23 HD109426NICHD NIH HHS R01 HD084819NICHD NIH HHS UG1 HD104252
6 · The paper itself

Abstract

objectiveEvaluate the relationship of neonatal unit level of care (LOC) and volume with mortality or morbidity in moderate-late preterm (MLP) (32-36 weeks' gestation) infants.

designRetrospective cohort study of 650,865 inborn MLP infants in 4976 hospitals-years using 2003-2015 linked administrative data from 4 states. Exposure was combined neonatal LOC and MLP annual volume. The primary outcome was death or morbidity (respiratory distress syndrome, severe intraventricular hemorrhage, necrotizing enterocolitis, sepsis, infection, pneumothorax, extreme length of stay) with components as secondary outcomes. Poisson regression models adjusted for patient characteristics with a random effect for unit were used.

resultsIn adjusted models, high-volume level 2 units had a lower risk of the primary outcome compared to low-volume level 3 units (aIRR 0.90 [95% CI 0.83-0.98] vs. aIRR 1.13 [95% CI 1.03-1.24], p < 0.001)

conclusionMLP infants had improved outcomes in high-volume level 2 units compared to low-volume level 3 units in adjusted analysis.

Indexed as

Hospitals, High-VolumeInfant, PrematureInfant, Premature, DiseasesFemaleGestational AgeHospitals, Low-VolumeHumansInfantInfant MortalityInfant, NewbornIntensive Care Units, NeonatalLength of StayMaleRespiratory Distress Syndrome, NewbornRetrospective StudiesUnited States

Identifiers

PMID38413758
PMCPMC11347722
OpenAlexW4392200455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.