ArticleScientific reports2024
Virtual non-iodine photon-counting CT-angiography for aortic valve calcification scoring.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- A scoping review of photon-counting detector computed tomography in cardiovascular imaging.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Multiphase aortic valve calcium scoring on true-non-contrast and calcium-preserving spectral reconstructions using dual-source photon-counting detector CT.European radiology · 2026Article
- Aortic Valve Calcium Scoring Using True and Virtual Non-Contrast Reconstructions on Photon-Counting CT with Differing Slice Increments: Impact on Calcium Severity Classifications.Tomography (Ann Arbor, Mich.) · 2025Article
- Spectral Imaging Techniques in Heart Disease Assessment Using Photon-Counting Detector Computed Tomography.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Quantification of abdominal aortic calcification using photon-counting CT angiography: an imaging biomarker for high-risk cardiovascular patients.La Radiologia medica · 2025Article
- Low-keV Virtual Monoenergetic Imaging for Bronchial Artery Visualization on Photon-Counting Detector Computed Tomography.Diagnostics (Basel, Switzerland) · 2025Article
- Beyond Cholesterol: Emerging Risk Factors in Atherosclerosis.Journal of clinical medicine · 2025Review
- Article
- Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.PloS one · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photon-counting detector (PCD)-CT allows for reconstruction of virtual non-iodine (VNI) images from contrast-enhanced datasets. This study assesses the diagnostic performance of aortic valve calcification scoring (AVCS) derived from VNI datasets generated with a 1st generation clinical dual-source PCD-CT. AVCS was evaluated in 123 patients (statistical analysis only comprising patients with aortic valve calcifications [n = 56; 63.2 ± 11.6 years]), who underwent contrast enhanced electrocardiogram-gated (either prospective or retrospective or both) cardiac CT on a clinical PCD system. Patient data was reconstructed at 70 keV employing a VNI reconstruction algorithm. True non-contrast (TNC) scans at 70 keV without quantum iterative reconstruction served as reference in all individuals. Subgroup analysis was performed in 17 patients who received both, prospectively and retrospectively gated contrast enhanced scans (n = 8 with aortic valve calcifications). VNI images with prospective/retrospective gating had an overall sensitivity of 69.2%/56.0%, specificity of 100%/100%, accuracy of 85.4%/81.0%, positive predictive value of 100%/100%, and a negative predictive value of 78.2%/75.0%. VNI images with retrospective gating achieved similar results. For both gating approaches, AVCS
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