ArticleTranslational psychiatry2024
Estrogen signaling in the dorsal raphe regulates binge-like drinking in mice.
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Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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0cells of the map it votes in
9citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- On the importance of including both sexes in animal studies - insights from home-cage monitoring.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Diosgenin activates ERα-dependent PI3K/AKT/GSK3β signaling to enhance brain-derived serotonin and alleviate postmenopausal bone loss.Journal of advanced research · 2026Article
- A discrete serotonergic circuit involved in the generation of tinnitus behavior.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner.Addiction neuroscience · 2025Article
- Midbrain ghrelin receptor signalling regulates binge drinking in a sex specific manner.Nature communications · 2025Article
- Dietary Soy Preserves Cognitive Function in Experimental Fetal Alcohol Spectrum Disorder: Role of Increased Signaling through Notch and Gonadotropin Releasing Hormone Networks.Journal of behavioral and brain science · 2025Article
- Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease.Molecular psychiatry · 2025Article
- Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 2 countries.
Valeria C Torres Irizarry *Division of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Bing Feng *Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, 70808, USA.ORCID 0000-0002-7403-8402
Xiaohua YangDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Nirali PatelDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID 0000-0003-1400-4398
Sarah SchaulDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Lucas IbrahimiDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Hui YeDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID 0000-0002-8473-0603
Pei LuoDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Leslie Carrillo-SáenzDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Penghua LaiDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID 0000-0001-6119-8194
Maya KotaDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.
Devin DixitDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID 0000-0001-9591-2173
Chunmei WangChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Amy W LasekCenter for Alcohol Research in Epigenetics and Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID 0000-0002-7099-2442
Yanlin HePennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, 70808, USA. Yanlin.He@pbrc.edu.ORCID 0000-0002-5471-9016
Pingwen XuDivision of Endocrinology, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, 60612, USA. pingwenx@uic.edu.ORCID 0000-0001-9363-4114
University of Illinois Chicago · USPennington Biomedical Research Center · USSouth China Agricultural University · CNChildren's Nutrition Research Center at Baylor College of Medicine · USVirginia Commonwealth University · US
Funding
Pilot Project Program P50AA022538 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2015 to 2026
$21.3MPilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2013 to 2026
$20.9MThe role of maternal obesity-driven inflammation and adverse pregnancy outcomes in a mouse model of preeclampsiaP20GM135002 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Timothy Allerton · 2020 to 2026
$18.4MRegulation of Excessive Alcohol Consumption by the Lmo-Alk AxisU01AA020912 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Amy Wolven Lasek · 2011 to 2026
$5.4MAlcohol Research Training in epigenetics and pathophysiology (ARTEP)T32AA026577 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2019 to 2026
$2.7MTestosterone and estrogen signaling pathways in the medial amygdala interact to control energy homeostasisR01DK123098 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XU, PINGWEN · 2020 to 2024
$2.5MGABA neurons in the ventromedial hypothalamus contribute to the counterregulatory responseR01DK129548 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Yanlin He · 2022 to 2026
$2.1MCompulsive Alcohol Drinking and Cortical Extracellular MatrixR01AA027231 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI LASEK, AMY WOLVEN · 2019 to 2023
$1.9MESTROGEN-INDUCIBLE PNNS ENHANCE EXCITATORY SYNAPTIC STRENGTH ONTO GABA NEURONS IN THE MEPD TO PREVENT OBESITY AND METABOLIC DYSREGULATIONR01DK136627 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Chunmei Wang · 2023 to 2026
$1.8MA TAP63 TRANSCRIPTIONAL AXIS CONTRIBUTES TO THE SEXUAL DIMORPHISM IN POMC NEURON FUNCTIONS AND ENERGY HOMEOSTASISK01DK119471 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WANG, CHUNMEI · 2019 to 2021
$391kEstrogen Signaling in the Ventromedial Hypothalamus Modulates Adipose Tissue Metabolic AdaptationF31DK132918 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TORRES IRIZARRY, VALERIA CECILIA · 2023 to 2024
$97kNIAAA NIH HHS P50 AA022538NIAAA NIH HHS R01 AA027231NIAAA NIH HHS T32 AA026577NIAAA NIH HHS U01 AA020912NIDDK NIH HHS F31 DK132918NIDDK NIH HHS K01 DK119471NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK123098NIDDK NIH HHS R01 DK129548NIDDK NIH HHS R01 DK136627NIGMS NIH HHS P20 GM135002
Abstract
Estrogens promote binge alcohol drinking and contribute to sex differences in alcohol use disorder. However, the mechanisms are largely unknown. This study aims to test if estrogens act on 5-hydroxytryptamine neurons in the dorsal raphe nucleus (5-HT
Indexed as
Binge DrinkingEstrogen Receptor alphaAnimalsDorsal Raphe NucleusEstrogen Receptor betaEstrogensEthanolFemaleMaleMiceSerotoninEstrogen Receptor alphaEstrogen Receptor betaEstrogensEthanolSerotonin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.