Evidence map›Paper›PMID 38413568›Full record

ArticleNature communications2024

In-vivo integration of soft neural probes through high-resolution printing of liquid electronics on the cranium.

Young-Geun Park, Yong Won Kwon, Chin Su Koh, Enji Kim, Dong Ha Lee, Sumin Kim, Jongmin Mun, Yeon-Mi Hong, Sanghoon Lee, Ju-Young Kim and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Multifunctional Liquid Metal for Biomimicry Application.Biomimetics (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Young-Geun Park *Department of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Yong Won Kwon *Department of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Chin Su Koh *Department of Neurosurgery, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Enji Kim *Department of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Dong Ha LeeDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Sumin KimDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Jongmin MunDepartment of Statistics and Data Science, Yonsei University, Seoul, 03722, South Korea.ORCID 0000-0003-1096-2994
Yeon-Mi HongDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.
Sanghoon LeeDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea.ORCID 0000-0002-0502-3370
Ju-Young KimCenter for Nanomedicine, Institute for Basic Science (IBS), Seoul, 03722, South Korea.ORCID 0000-0001-5807-7017
Jae-Hyun LeeCenter for Nanomedicine, Institute for Basic Science (IBS), Seoul, 03722, South Korea.ORCID 0000-0002-9236-157X
Hyun Ho JungDepartment of Neurosurgery, Yonsei University College of Medicine, Seoul, 03722, South Korea. junghh@yuhs.ac.ORCID 0000-0002-8289-564X
Jinwoo CheonCenter for Nanomedicine, Institute for Basic Science (IBS), Seoul, 03722, South Korea. jcheon@yonsei.ac.kr.ORCID 0000-0001-8948-5929
Jin Woo ChangDepartment of Neurosurgery, Korea University Anam Hospital, Seoul, 02841, South Korea. jchang@yuhs.ac.ORCID 0000-0002-2717-0101
Jang-Ung ParkDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, South Korea. jang-ung@yonsei.ac.kr.ORCID 0000-0003-1522-4958
Yonsei University · KRKorea University Medical Center · KR

Funding

Ministry of Trade, Industry and Energy, Korea | Korea Evaluation Institute of Industrial Technology (KEIT) 20013621National Research Foundation of Korea (NRF) 2020R1A5A1019131National Research Foundation of Korea (NRF) 2021M3D1A2049914National Research Foundation of Korea (NRF) 2022R1A5A6000846National Research Foundation of Korea (NRF) 2023R1A2C2006257
6 · The paper itself

Abstract

Current soft neural probes are still operated by bulky, rigid electronics mounted to a body, which deteriorate the integrity of the device to biological systems and restrict the free behavior of a subject. We report a soft, conformable neural interface system that can monitor the single-unit activities of neurons with long-term stability. The system implements soft neural probes in the brain, and their subsidiary electronics which are directly printed on the cranial surface. The high-resolution printing of liquid metals forms soft neural probes with a cellular-scale diameter and adaptable lengths. Also, the printing of liquid metal-based circuits and interconnections along the curvature of the cranium enables the conformal integration of electronics to the body, and the cranial circuit delivers neural signals to a smartphone wirelessly. In the in-vivo studies using mice, the system demonstrates long-term recording (33 weeks) of neural activities in arbitrary brain regions. In T-maze behavioral tests, the system shows the behavior-induced activation of neurons in multiple brain regions.

Indexed as

ElectronicsNeuronsAnimalsBrainMetalsMicePrinting, Three-DimensionalSkullMetals

Identifiers

PMID38413568
PMCPMC10899244
OpenAlexW4392200113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.