Evidence map›Paper›PMID 38413189›Full record

ArticleJournal of medical ethics2025

Is the UN receiving ethical approval for its research with human participants?

Robert James Torrance, Maru Mormina, Sadath Sayeed, Anthony Kessel, Chang Ho Yoon, Beniamino Cislaghi

Abstract read
In one paragraph

Article in Journal of medical ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert James TorranceLondon School of Hygiene and Tropical Medicine Faculty of Public Health and Policy, London, UK robert.torrance@lshtm.ac.uk.ORCID 0000-0003-1712-0722
Maru MorminaAfrican Centre of Epistemology and Philosophy of Science, University of Johannesburg, Johannesburg, South Africa.
Sadath SayeedDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Anthony KesselLondon School of Hygiene and Tropical Medicine Faculty of Public Health and Policy, London, UK.
Chang Ho YoonUniversity of Oxford Big Data Institute, Oxford, UK.
Beniamino CislaghiLondon School of Hygiene and Tropical Medicine Faculty of Public Health and Policy, London, UK.

Funding

Wellcome TrustWellcome Trust 102176/B/13/Z203132
6 · The paper itself

Abstract

This paper examines the institutional mechanisms supporting the ethical oversight of human participant research conducted by the United Nations (UN). The UN has served an instrumental role in shaping international standards on research ethics, which invariably require ethical oversight of all research studies with human participants. The authors' experiences of conducting research collaboratively with UN agencies, in contrast, have led to concern that the UN frequently sponsors, or participates in, studies with human participants that have not received appropriate ethical oversight. It is argued that the institutional mechanisms in place to prevent research with human participants from being undertaken by the UN without ethical oversight do not, at present, extend substantively beyond the provision of guidelines and online training offered by a minority of UN bodies. The WHO and UNICEF are identified as notable exceptions, having implemented various measures to prevent health research with human participants from being undertaken without ethical oversight. Yet, it is highlighted that the WHO and UNICEF are not the only UN bodies that undertake health research with human participants and there are countless actors under the umbrella of the UN system that are regularly involved in non-health research with human participants. Arguments for the pursuit of the highest standard of ethical oversight by UN bodies are presented. Moving forward, the paper asks the question: is it time for the UN to set the standards for the oversight of ethical oversight?

Indexed as

Biomedical ResearchEthics, ResearchHuman ExperimentationResearch SubjectsUnited NationsEthics Committees, ResearchHumansEthicsEthics CommitteesEthics- ResearchPolicy

Identifiers

PMID38413189
PMCPMC11877110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.