Evidence map›Paper›PMID 38412514›Full record

ArticleOpen forum infectious diseases2024

Creation and Validation of an Automated Registry for Outpatient Parenteral Antibiotics.

Joseph Canterino, Maricar Malinis, Jing Liu, Nitu Kashyap, Cynthia Brandt, Amy Justice

Open access · goldAbstract readComment
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. A bundle of the top 10 OPAT publications in 2024.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Review
  4. Management of outpatient parenteral antibiotic therapy: a United States-based multi-center survey.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  5. Article
  6. Article
  7. Models of Outpatient Parenteral Antimicrobial Therapy Care: One Size May Not Fit All.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joseph CanterinoYale University School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-3692-7521
Maricar MalinisYale University School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-5720-9994
Jing LiuYale-New Haven Health, New Haven, Connecticut, USA.
Nitu KashyapYale University School of Medicine, New Haven, Connecticut, USA.
Cynthia BrandtVeterans Affairs Heathcare System, West Haven CT; Yale University School of Medicine, New Haven, Connecticut, USA.
Amy JusticeVeterans Affairs Heathcare System, West Haven CT; Yale University School of Medicine, New Haven, Connecticut, USA.
Yale University · USYale New Haven Health System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Existing outpatient parenteral antibiotic therapy (OPAT) registries are resource intensive, and OPAT programs struggle to produce objective data to show the value of their work. We describe the building and validation of an automated OPAT registry within our electronic medical record and provide objective data on the value of the program. Variables and outcomes include age, sex, race, ethnicity, primary insurance payor, antibiotic names, infection syndromes treated, discharge disposition, 30-day all-cause readmission and death rates, complications, and an estimate of the hospital days saved. Records for 146 OPAT episodes were reviewed manually to validate the registry. Data were displayed in a dashboard within the electronic medical record. Over the 4-year time frame, our registry collected 3956 unique patients who completed 4710 episodes (approximately 1200 episodes per year). A total of 400 complications during OPAT were identified. All variables had an accuracy of >90% on validation. The OPAT program resulted in a reduction in hospital length of stay by 88 820 days, or roughly 22 000 days per year. We intend our registry to serve as a blueprint for similar OPAT programs with limited administrative resources. Wider application of our system would allow for easier aggregation and comparisons of OPAT practice and address the lack interinstitutional standardization of OPAT data and outcomes.

Indexed as

DashboardinformaticsOPATregistryvalue

Identifiers

PMID38412514
PMCPMC10866572
OpenAlexW4390733308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.