Evidence map›Paper›PMID 38412383›Full record

ArticleJCO clinical cancer informatics2024

Path-BigBird: An AI-Driven Transformer Approach to Classification of Cancer Pathology Reports.

Mayanka Chandrashekar, Isaac Lyngaas, Heidi A Hanson, Shang Gao, Xiao-Cheng Wu, John Gounley

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mayanka ChandrashekarAdvanced Computing for Health Sciences Section, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN.ORCID 0000-0002-3697-5972
Isaac LyngaasAdvanced Computing for Life Science & Engineering, National Center for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, TN.ORCID 0000-0002-1682-4309
Heidi A HansonAdvanced Computing for Health Sciences Section, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN.
Shang GaoAdvanced Computing for Health Sciences Section, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN.ORCID 0000-0003-1803-1457
Xiao-Cheng WuLouisiana Tumor Registry, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA.ORCID 0000-0003-3663-5027
John GounleyAdvanced Computing for Health Sciences Section, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN.

Funding

POLICY & ENVIRONMENTAL APPROACHES & COMMUNITY-CLINICAL LINKAGES IN CANCER PROGRAMU58DP003907 · DP · UNIVERSITY OF KENTUCKY · PI TUCKER, THOMAS C · 2012 to 2014
$3.8M
Healthy Youth Development Research and Training CenterU48DP000063 · DP · UNIVERSITY OF MINNESOTA TWIN CITIES · PI RESNICK, MICHAEL DAVID · 2004 to 2008
$2.2M
NCCDPHP CDC HHS U48 DP000063NCCDPHP CDC HHS U58 DP003907NCI NIH HHS HHSN261201000041CNCI NIH HHS HHSN261201000041INCI NIH HHS HHSN261201800001CNCI NIH HHS HHSN261201800004CNCI NIH HHS HHSN261201800013INCI NIH HHS HHSN261201800016CNCI NIH HHS HHSN261201800016INCI NIH HHS HHSN261201800041C
6 · The paper itself

Abstract

purposeSurgical pathology reports are critical for cancer diagnosis and management. To accurately extract information about tumor characteristics from pathology reports in near real time, we explore the impact of using domain-specific transformer models that understand cancer pathology reports.

methodsWe built a pathology transformer model, Path-BigBird, by using 2.7 million pathology reports from six SEER cancer registries. We then compare different variations of Path-BigBird with two less computationally intensive methods: Hierarchical Self-Attention Network (HiSAN) classification model and an off-the-shelf clinical transformer model (Clinical BigBird). We use five pathology information extraction tasks for evaluation: site, subsite, laterality, histology, and behavior. Model performance is evaluated by using macro and micro

resultsWe found that Path-BigBird and Clinical BigBird outperformed the HiSAN in all tasks. Clinical BigBird performed better on the

conclusionThe Path-BigBird pathology transformer model improves automated information extraction from pathology reports. Although Path-BigBird outperforms Clinical BigBird and HiSAN, these less computationally expensive models still have utility when resources are constrained.

Indexed as

NeoplasmsArtificial IntelligenceHumansInformation Storage and RetrievalRegistries

Identifiers

PMID38412383
PMCPMC10904099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.