ArticleNucleic acids research1985
Molecular cloning of human apolipoprotein B cDNA.
Article in Nucleic acids research, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Serologic laboratory findings in malignancy.Rheumatic diseases clinics of North America · 2011Review
- Improved approach to identify cancer-associated autoantigens.Autoimmunity reviews · 2005Review
- Catabolic rate of low density lipoprotein is influenced by variation in the apolipoprotein B gene.The Journal of clinical investigation · 1988Article
- Genetic analysis of a kindred with familial hypobetalipoproteinemia. Evidence for two separate gene defects: one associated with an abnormal apolipoprotein B species, apolipoprotein B-37; and a second associated with low plasma concentrations of apolipoprotein B-100.The Journal of clinical investigation · 1987Article
- The complete sequence and structural analysis of human apolipoprotein B-100: relationship between apoB-100 and apoB-48 forms.The EMBO journal · 1986Article
- Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- The isolation of genomic recombinants for the human apolipoprotein B gene and the mapping of three common DNA polymorphisms of the gene--a useful marker for human chromosome 2.Human genetics · 1986Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper we describe the isolation of cDNA clones which code for parts of apolipoprotein B (apoB). The clones were obtained by immunoscreening of an expression library (lambda gt 11) derived from a human hepatoma cell line (Hep G2). The relationship between positive clones and apoB was established with immunochemical techniques using polyclonal as well as monoclonal antibodies. Recombinants, expressing nonoverlapping regions of apoB are described, all hybridizing with a very large mRNA (approximately 20,000 bases long). The nucleotide sequence obtained predicts a primary protein structure with a composition suitable for the formation of stretches of an amphipatic alpha-helix.
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