Evidence map›Paper›PMID 38411670›Full record

ArticleInternational archives of occupational and environmental health2024

Environmental exposure to per- and polyfluoroalkyl substances mixture and asthma in adolescents.

Yi-Fan Wang, Li Li, Xu Wang, Ya-Nan Yun, Xue-Lin Wang, En-Yang He, Ming-Kun Song, Xue-Hong Xia, Ying-Xue Zou

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Article in International archives of occupational and environmental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yi-Fan Wang *Clinical School of Paediatrics, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-5946-1798
Li Li *Clinical School of Paediatrics, Tianjin Medical University, Tianjin, China.
Xu Wang *Clinical School of Paediatrics, Tianjin Medical University, Tianjin, China.
Ya-Nan YunDepartment of Pulmonology, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Machang Compus, 225 Machang Road, Hexi District, Tianjin, 300074, China.
Xue-Lin WangDepartment of Pulmonology, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Machang Compus, 225 Machang Road, Hexi District, Tianjin, 300074, China.
En-Yang HeClinical School of Paediatrics, Tianjin Medical University, Tianjin, China.
Ming-Kun SongTianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300070, China.
Xue-Hong XiaClinical School of Paediatrics, Tianjin Medical University, Tianjin, China.
Ying-Xue ZouDepartment of Pulmonology, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Machang Compus, 225 Machang Road, Hexi District, Tianjin, 300074, China. tmuzouyingxue@163.com.

Funding

Tianjin Children's Hospital TJYXZDXK-040A
6 · The paper itself

Abstract

backgroundPrevious epidemiological studies about the relationship between per- and polyfluoroalkyl substances (PFAS) concentrations and adolescent asthma have typically examined single PFAS, without considering the mixtures effects of PFAS.

methodsUsing data from the 2013-2018 National Health and Nutrition Examination Survey (NHANES), 886 adolescents aged 12-19 years were included in this study. We explored the association between PFAS mixture concentrations and adolescent asthma using weighted quantile sum (WQS) regression and Bayesian kernel machine regression (BKMR) models, respectively.

resultsAfter adjusting for confounders, the results of the WQS regression and BKMR models were consistent, with mixed exposure to the five PFAS not significantly associated with asthma in all adolescents. The association remained nonsignificant in the subgroup analysis by sex.

conclusionsOur study demonstrated no significant association between mixed exposure to PFAS and adolescent asthma, and more large cohort studies are needed to confirm this in the future.

Indexed as

AsthmaFluorocarbonsAdolescentBayes TheoremEnvironmental ExposureHumansNutrition SurveysFluorocarbonsAdolescentsAsthmaMixture effectsPer- and polyfluoroalkyl substances

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.