Evidence map›Paper›PMID 38411110›Full record

ArticleMicrobiology spectrum2024

Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms.

Ashlan J Kunz Coyne, Kyle Stamper, Callan Bleick, Razieh Kebriaei, Susan M Lehman, Michael J Rybak

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. mSphere · 2026
    Article
  4. Review
  5. Impact ofAntimicrobial agents and chemotherapy · 2026
    Article
  6. Article
  7. Comprehensive characterization ofCurrent research in food science · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Editorial: Bacteriophage therapy in orthopedics-Key questions and emerging answers.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ashlan J Kunz CoyneAnti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.ORCID 0000-0002-4891-8625
Kyle StamperAnti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Callan BleickAnti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Razieh KebriaeiAnti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Susan M LehmanCenter for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Michael J RybakAnti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.ORCID 0000-0003-2220-0081
Eugene Applebaum College of Pharmacy and Health Sciences · USCenter for Biologics Evaluation and Research · US

Funding

Mechanisms and Circumvention of Daptomycin Resistance in Streptococcus mitisR01AI130056 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI BAYER, ARNOLD S · 2018 to 2022
$2.4M
Anti-biofilm activity of bacteriophage-antibiotic combinations against MRSAR21AI163726 · NIAID · WAYNE STATE UNIVERSITY · PI RYBAK, MICHAEL JOSEPH · 2021 to 2022
$424k
NIAID NIH HHS AAI20020-001-00000NIAID NIH HHS R01 AI130056NIAID NIH HHS R21 AI163726
6 · The paper itself

Abstract

Methicillin-resistant IMPORTANCE: The prevalence of biofilm-associated medical device infections caused by methicillin-resistant

Indexed as

BenzimidazolesCarboxylic AcidsDaptomycinMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnti-Bacterial AgentsBiofilmsCeftarolineCephalosporinsHumansMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsBenzimidazolesCarboxylic AcidsCeftarolineCephalosporinsDaptomycinmethyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo(d)imidazole-5-carboxylatebacterial synergybactericidal activitybacteriophagebiofilmceftarolinedaptomycinin vitro modelsmedical device infectionsMRSAphage-antibiotic combinations

Identifiers

PMID38411110
PMCPMC10986480
OpenAlexW4392199683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.