Evidence map›Paper›PMID 38411084›Full record

ArticleApplied and environmental microbiology2024

Prebiotic effect of galacto-

Chiaki Matsuzaki, Hiroki Takagi, Sorachi Saiga, Yuun Kinoshita, Misako Yamaguchi, Yasuki Higashimura, Kenji Yamamoto, Masanori Yamaguchi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Progress in interventions for vaginal microecology.Frontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chiaki MatsuzakiResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.ORCID 0000-0001-6035-0481
Hiroki TakagiDepartment of Production Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Sorachi SaigaDepartment of Production Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Yuun KinoshitaResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Misako YamaguchiDepartment of Organic Bio Chemistry, Faculty of Education, Wakayama University, Wakayama, Japan.
Yasuki HigashimuraDepartment of Food Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Kenji YamamotoCenter for Innovative and Joint Research, Wakayama University, Wakayama, Japan.
Masanori YamaguchiDepartment of Organic Bio Chemistry, Faculty of Education, Wakayama University, Wakayama, Japan.
Ishikawa Prefectural University · JPWakayama University · JP

Funding

MEXT | JST | Adaptable and Seamless Technology Transfer Program through Target-Driven R and D (A-STEP) JPMJTR20UG
6 · The paper itself

Abstract

Galacto- IMPORTANCE: Specific members of lactic acid bacteria, which are commonly used as probiotics, possess therapeutic properties that are vital for human health enhancement by producing immunomodulatory metabolites such as exopolysaccharides, short-chain fatty acids, and bacteriocins. The long residence time of probiotic lactic acid bacteria in the GI tract prolongs their beneficial health effects. Moreover, the colonization property is also desirable for the application of probiotics in mucosal vaccination to provoke a local immune response. In this study, we found that GNB could enhance the beneficial properties of intestinal lactic acid bacteria that inhabit the human GI tract, stimulating acetate production and promoting intestinal colonization. Our findings provide a rationale for the addition of GNB to lactic acid bacteria-based functional foods. This has also led to the development of therapeutics supported by more rational prebiotic and probiotic selection, leading to an improved healthy lifestyle for humans.

Indexed as

LactobacillalesProbioticsAcetatesAnimalsBacteriaDisaccharidasesHumansMicePrebioticsAcetatesDisaccharidasesgalacto-N-biosePrebioticsacetategalacto-N-bioseGNBintestinal colonizationlactic acid bacteriaLacticaseibacillus rhamnosusprebioticprobiotics

Identifiers

PMID38411084
PMCPMC10952502
OpenAlexW4392199041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.