Evidence map›Paper›PMID 38411048›Full record

ArticleJournal of bacteriology2024

Sphingosine induction of the

Jacob R Mackinder, Lauren A Hinkel, Kristin Schutz, Korin Eckstrom, Kira Fisher, Matthew J Wargo

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. A genome-wide screen inJournal of bacteriology · 2026
    Article
  2. Article
  3. Sphingosine synergizes with polymyxin antibiotics againstMicrobiology (Reading, England) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Virulence · 2025
    Article
  8. Article
  9. The fatty acid synthesis geneMicrobiology spectrum · 2025
    Article
  10. Sphingosine-mediated death ofInfection and immunity · 2025
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jacob R MackinderDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Lauren A HinkelDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Kristin SchutzDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Korin EckstromDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Kira FisherDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Matthew J WargoDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.ORCID 0000-0001-5659-749X
University of Vermont · US

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI Robert A Koza · 2017 to 2026
$51.6M
Multidisciplinary Training in Lung BiologyT32HL076122 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G, POYNTER, MATTHEW E · 2004 to 2023
$6.1M
The role of potable water as the pre-infection niche for Pseudomonas aeruginosaR21AI137453 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2019 to 2020
$429k
Regulation of the virulence factor PlcH in Pseudomonas aeruginosaR56AI173006 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2023 to 2023
$379k
NIAID NIH HHS R21 AI137453NIAID NIH HHS R56 AI173006NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

Hemolytic phospholipase C, PlcH, is an important virulence factor for IMPORTANCE: PlcH is a secreted phospholipase C/sphingomyelinase that is important for the virulence of

Indexed as

BetainePseudomonas aeruginosaCeramidasesSphingomyelin PhosphodiesteraseSphingosineType C PhospholipasesBetaineCeramidasesSphingomyelin PhosphodiesteraseSphingosineType C Phospholipaseslipidpathogenesissphingolipidtranscriptional regulationvirulence

Identifiers

PMID38411048
PMCPMC10955842
OpenAlexW4392199649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.