Evidence map›Paper›PMID 38410939›Full record

ArticleJournal of the American Heart Association2024

Prospective Associations of Accelerometer-Measured Machine-Learned Sedentary Behavior With Death Among Older Women: The OPACH Study.

Steve Nguyen, John Bellettiere, Blake Anuskiewicz, Chongzhi Di, Jordan Carlson, Loki Natarajan, Michael J LaMonte, Andrea Z LaCroix

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Examining the relationship between D3Cr muscle mass, physical performance, and functional limitation in postmenopausal women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Association of wearableZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  3. Adherence to 24-hour movement guidelines and mortality risks in US cancer survivors: a national cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Steve NguyenDivision of Epidemiology Herbert Wertheim School of Public Health, University of California San Diego La Jolla CA USA.ORCID 0000-0002-5193-7042
John BellettiereDivision of Epidemiology Herbert Wertheim School of Public Health, University of California San Diego La Jolla CA USA.ORCID 0000-0002-7167-3048
Blake AnuskiewiczDivision of Epidemiology Herbert Wertheim School of Public Health, University of California San Diego La Jolla CA USA.ORCID 0000-0002-6460-3586
Chongzhi DiDivision of Public Health Sciences Fred Hutchinson Cancer Center Seattle WA USA.ORCID 0000-0002-1371-581X
Jordan CarlsonCenter for Children's Healthy Lifestyles and Nutrition, Children's Mercy Kansas City Kansas City MO USA.ORCID 0000-0002-6008-7983
Loki NatarajanDivision of Epidemiology Herbert Wertheim School of Public Health, University of California San Diego La Jolla CA USA.ORCID 0000-0001-5719-828X
Michael J LaMonteDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions University at Buffalo - SUNY Buffalo NY USA.ORCID 0000-0002-6669-5242
Andrea Z LaCroixDivision of Epidemiology Herbert Wertheim School of Public Health, University of California San Diego La Jolla CA USA.ORCID 0000-0002-9532-976X

Funding

WOMEN'S HEALTH INITIATIVE - CLINICAL COORDINATING CENTER: TASK AREA B - LONG LIFE STUDY VISIT 2 LIMITED HOME VISIT75N92021D00001 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ANDERSON, GARNET L. · 2021 to 2025
$52.0M
University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Sedentary Behaviour Interrupted: Acute, medium and long-term effects on biomarkers of healthy aging, physical function and mortalityP01AG052352 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACROIX, ANDREA Z. · 2017 to 2022
$9.0M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A275N92021D00002 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2021 to 2025
$6.9M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00004 · NHLBI · STANFORD UNIVERSITY · PI STEFANICK, MARCIA · 2021 to 2025
$6.5M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00003 · NHLBI · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA · 2021 to 2025
$5.0M
Objective Physical Activity and Cardiovascular Health in Women Aged 80 and OlderR01HL105065 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LACROIX, ANDREA Z. · 2011 to 2014
$5.0M
Statistical methods for analyzing objectively measured physical activity dataR01HL130483 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Chongzhi Di · 2016 to 2026
$4.4M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI VITOLINS, MARA · 2021 to 2025
$4.2M
Novel computational techniques to detect the relationship between sitting patterns and metabolic syndrome in existing cohort studies.R01DK114945 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NATARAJAN, LOKI · 2018 to 2021
$2.6M
Improving the Health of Aging Women and Men.T32AG058529 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACROIX, ANDREA Z. · 2019 to 2023
$1.2M
Plasma proteomic signatures of physical activity and Alzheimer's disease and related dementiasK99AG082863 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NGUYEN, STEVE · 2023 to 2024
$206k
NCATS NIH HHS UL1 TR001412NHLBI NIH HHS 75N92021D00001NHLBI NIH HHS 75N92021D00002NHLBI NIH HHS R01 HL105065NHLBI NIH HHS R01 HL130483NIA NIH HHS K99 AG082863NIA NIH HHS P01 AG052352NIA NIH HHS T32 AG058529NIDDK NIH HHS R01 DK114945WHI NIH HHS 75N92021D00003WHI NIH HHS 75N92021D00004WHI NIH HHS 75N92021D00005
6 · The paper itself

Abstract

backgroundSedentary behavior is a recognized mortality risk factor. The novel and validated convolutional neural network hip accelerometer posture algorithm highly accurately classifies sitting and postural changes compared with accelerometer count cut points. We examined the prospective associations of convolutional neural network hip accelerometer posture-classified total sitting time and mean sitting bout duration with all-cause and cardiovascular disease (CVD) death. METHODS AND

resultsWomen (n=5856; mean±SD age, 79±7 years; 33% Black women, 17% Hispanic or Latina women, 50% White women) in the Women's Health Initiative Objective Physical Activity and Cardiovascular Health (OPACH) Study wore the ActiGraph GT3X+ for ~7 days from May 2012 to April 2014 and were followed through February 19, 2022 for all-cause and CVD death. The convolutional neural network hip accelerometer posture algorithm classified total sitting time and mean sitting bout duration from GT3X+ output. Over follow-up (median, 8.4 years; range, 0.1-9.9), there were 1733 deaths (632 from CVD). Adjusted Cox regression hazard ratios (HRs) comparing women in the highest total sitting time quartile (>696 min/d) to those in the lowest (<556.0 min/d) were 1.57 (95% CI; 1.35-1.83;

conclusionsHigher total sitting time and longer mean sitting bout duration are associated with higher all-cause and CVD mortality risk among older women. These data support interventions aimed at reducing both total sitting time and interrupting prolonged sitting.

Indexed as

Cardiovascular DiseasesSedentary BehaviorAccelerometryAgedAged, 80 and overExerciseFemaleHumansTime Factorsagingepidemiologypublic healthwomen's health

Identifiers

PMID38410939
PMCPMC10944026

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.