ArticleERJ open research2024
A phase 4 multicentre, 2×2 factorial randomised, double-blind, placebo-controlled trial to investigate the efficacy and safety of tobramycin inhalation solution for
Registry-linked trialOpen access · goldAbstract read
In one paragraph
Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06760273 (Extended Observational Study on the Long-term Impact of Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Patients With Bronchiectasis), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Extended Observational Study on the Long-term Impact of Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Patients With Bronchiectasis: The ERASE II Study
Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.
- The European respiratory society guideline for adult bronchiectasis 2025: summary and implementation guide for primary care.NPJ primary care respiratory medicine · 2026Guideline
- Inhaled tobramycin for chronic pseudomonas aeruginosa infection in non-cystic fibrosis bronchiectasis: an updated systematic review and meta-analysis.BMC pulmonary medicine · 2026Pooled it
- Treatable traits-based management of bronchiectasis: moving from theory to clinical practice.Chinese medical journal pulmonary and critical care medicine · 2026Review
- Mechanism, Efficacy, and Safety of Natural Antibiotics.Antibiotics (Basel, Switzerland) · 2025Review
- Phenotypes and endotypes in bronchiectasis: a narrative review of progress toward precision medicine.Journal of thoracic disease · 2025Review
- Pulmonary Delivery of Antibiotics to the Lungs: Current State and Future Prospects.Pharmaceutics · 2025Review
- Microbiome and its role in bronchiectasis.Therapeutic advances in respiratory diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 20 institutions in 3 countries.
Yong-Hua GaoDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-8140-1679
Hai-Wen LuDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Hui-Zhen ZhengDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Chao CaoDepartment of Respiratory Medicine, The Affiliated Hospital of School of Medicine, Ningbo University, Ningbo, China.
De-Jie ChuDepartment of Respiratory Medicine, The Eighth People's Hospital of Shanghai, Shanghai, China.
Hong FanDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Xiao-Yun FanDepartment of Geriatric Respiratory and Critical Care, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Hong-Yan GuDepartment of Pulmonary and Critical Care Medicine, The Sixth People's Hospital of Nantong, Nantong, China.
Wei-Jie GuanState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhi-Jun JieDepartment of Respiratory and Critical Care Medicine, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Yang JinDepartment of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0003-2409-7073
Wen LiKey Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Yu-Ping LiDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Yuan-Yuan LiDepartment of Respiratory Medicine, Branch of National Clinical Research Center for Respiratory Disease, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Lin LiuDepartment of Respiratory Medicine, Guizhou Provincial People Hospital, Guiyang City, China.
Xue-Dong LiuTsingtao Municipal Hospital, Qingdao, China.
Hong LuoDepartment of Pulmonary and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-9501-651X
Xiao-Dong LvDepartment of Respiration, The First Hospital of Jiaxing, Jiaxing, China.
Wei-Qiang MoDepartment of Respiration, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
Yuan-Lin SongDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Dao-Xin WangDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ling-Wei WangPulmonary and Critical Care Department, Shenzhen People's Hospital, Shenzhen Institute of Respiratory Diseases, Shenzhen, China.
Chang-Zheng WangDepartment of Respiratory Medicine, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Min XieDepartment of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0003-4052-1647
Min ZhangDepartment of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cui-Xia ZhengDepartment of Respiratory Medicine, Shanghai Yangpu District Central Hospital, Tongji University, Shanghai, China.
Bei MaoDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0003-0417-7607
James D ChalmersDivision of Molecular and Clinical Medicine, University of Dundee, Dundee, UK.
Jie-Ming QuDepartment of Respiratory and Critical Care Medicine, Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jin-Fu XuDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-8039-8973
Tongji University · CNCentral South University · CNFudan University · CNShanghai Jiao Tong University · CNAnhui Medical University · CNChongqing Medical University · CNDalian Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNFirst Hospital of Jiaxing · CNGuizhou Provincial People's Hospital · CNJiaxing University · CNNantong University · CNNanyang Technological University · SGNingbo University · CNQingdao University · CNSecond Affiliated Hospital of Zhejiang University · CNShanghai Eighth People Hospital · CNShenZhen People’s Hospital · CNSichuan University · CNTongji Hospital · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Read underepoch 390
Registered trials
NCT06760273ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.