ArticleAnnual review of fluid mechanics2019
Blood flow and transport in the human placenta.
Article in Annual review of fluid mechanics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 60 citations in OpenAlex.
- Regulation of PDGF-BB signaling in placental pericytes by soluble PDGFRβ isoforms: implications for fetoplacental vascular development.Angiogenesis · 2026Article
- The human placenta development and anatomy.Archives of gynecology and obstetrics · 2026Review
- Early identification of umbilical blood flow restriction and maternal placental hypoperfusion with photoacoustic imaging.Photoacoustics · 2026Article
- Diagnostic performance of urinary adipsin as a screening biomarker for pre-eclampsia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Modelling maternal cardiovascular adaptation to pregnancy: a scoping review.BMC pregnancy and childbirth · 2025Article
- A functional shunt in the umbilical cord: the role of coiling in solute and heat transfer.Journal of the Royal Society, Interface · 2025Article
- High-resolution MRI reveals uteroplacental flow dynamics in a 3D-printed human placental cotyledon model.Science advances · 2025Article
- 3D multiscale characterization of the human placenta: Bridging anatomy and histology by X-ray phase-contrast tomography.PNAS nexus · 2025Article
- Plasma From Older Children in Malawi Inhibits Plasmodium falciparum Binding in 3-Dimensional Brain Microvessels.The Journal of infectious diseases · 2024Article
- A flexible generative algorithm for growing in silico placentas.PLoS computational biology · 2024Article
- A genetically small fetus impairs placental adaptations near term.Disease models & mechanisms · 2024Article
- The Endometrial Stem/Progenitor Cells and Their Niches.Stem cell reviews and reports · 2024Review
- Unveiling the human fetal-maternal interface during the first trimester: biophysical knowledge and gaps.Frontiers in cell and developmental biology · 2024Review
- Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) model.PLoS pathogens · 2023Article
- Recasting Current Knowledge of Human Fetal Circulation: The Importance of Computational Models.Journal of cardiovascular development and disease · 2023Review
- Article
- Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media.Interface focus · 2022Article
- Application of a multicomponent model of convectional reaction-diffusion to description of glucose gradients in a neurovascular unit.Frontiers in physiology · 2022Article
- A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta.Journal of the Royal Society, Interface · 2021Article
- Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The placenta is a multi-functional organ that exchanges blood gases and nutrients between a mother and her developing fetus. In humans, fetal blood flows through intricate networks of vessels confined within villous trees, the branches of which are bathed in pools of maternal blood. Fluid mechanics and transport processes play a central role in understanding how these elaborate structures contribute to the function of the placenta, and how their disorganization may lead to disease. Recent advances in imaging and computation have spurred significant advances in simulations of fetal and maternal flows within the placenta, across a range of lengthscales. Models describe jets of maternal blood emerging from spiral arteries into a disordered and deformable porous medium, and solute uptake by fetal blood flowing through elaborate three-dimensional capillary networks. We survey recent developments and emerging challenges in modeling flow and transport in this complex organ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.