Evidence map›Paper›PMID 38410463›Full record

ArticleResearch square2024

Generalized and COVID related anxiety as risk factors for health outcomes among adolescents with HIV during COVID-19 in Tanzania.

Hellen Siril, David Gitagno, Sylvia Kaaya, Matthew Caputo, Lisa Hirschhorn, Tumaini Nyamuhanga, Rachel Mtei, Charles Festo, Claudia Hawkins

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hellen SirilMuhimbili University of Health and Allied Sciences.
David GitagnoMuhimbili University of Health and Allied Sciences.
Sylvia KaayaMuhimbili University of Health and Allied Sciences.
Matthew CaputoNorthwestern University.
Lisa HirschhornNorthwestern University.
Tumaini NyamuhangaMuhimbili University of Health and Allied Sciences.
Rachel MteiMuhimbili University of Health and Allied Sciences.
Charles FestoManagement and Development for Health.
Claudia HawkinsNorthwestern University.
Muhimbili University of Health and Allied Sciences · TZManagement and Development for Health · TZ

Funding

Building capacity for patient-centered outcomes research to improve the quality and impact of HIV care in TanzaniaD43TW010946 · FIC · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAWKINS, CLAUDIA A, HIRSCHHORN, LISA · 2019 to 2023
$1.7M
FIC NIH HHS D43 TW010946
6 · The paper itself

Abstract

The COVID-19 pandemic and associated prevention strategies caused widespread interruptions to care and treatment for people living with HIV. Adolescents living with HIV (AWHIV) were particularly vulnerable to poor mental and physical health during COVID-19. We assessed the burden of generalized and COVID-19-related anxiety and associations with adherence to HIV care and treatment and viral load suppression (VLS) among AWHIV during the peak of the COVID-19 pandemic in Tanzania. Methods: This cross-sectional study was conducted among AWHIV aged 15-19 years attending 10 clinics in Dar es Salaam from April 2022-February 2023. Study participants completed a self-administered questionnaire including Generalized Anxiety Disorder (GAD), COVID-19-related anxiety, and other psychosocial and physical health and support measures. HIV visit adherence, viral load and sociodemographic data were abstracted from patient health records. Results: 658 AWHIV (52% male) were included in this analysis. Most (86%) had been on antiretroviral treatment (ART) for at least four years, 55% attended at least 75% of their scheduled clinic visits, and 78% were HIV virologically suppressed. The median GAD and COVID-19-related anxiety scores were 2 (IQR: 0-5, and 26 (IQR: 13-43; respectively. Only 2% scored moderate-severe generalized anxiety (score 10-21). We found no significant associations between COVID-19-related anxiety or GAD and visit adherence. Higher GAD was inversely associated with VLS (adjusted odds ratio (AOR): 0.89 (95% CI 0.81, 0.98)). Female gender and higher quality of physical life were significantly associated with VLS. Conclusion: Low levels of generalized and COVID-19 related anxiety were reported among Tanzanian AWHIV. Integrating screening and management of generalized anxiety screening into HIV care for AWHIV could improve VLS among this population.

Indexed as

AdolescentsAnxietyclinic visitsCOVID-19 pandemicDepressionHIVViral suppression

Identifiers

PMID38410463
PMCPMC10896391
OpenAlexW4391878741

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.