Evidence map›Paper›PMID 38410304›Full record

ReviewCureus2024

Alpha-2 Agonists in Children and Adolescents With Post-traumatic Stress Disorder: A Systematic Review.

Amit Jagtiani, Raghu Gandhi, Akshat Banga, Jacquetta Blacker, Riecha Joshi, Bhaswanth Bollu, Rahul Kashyap

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Guanfacine as an Adjunct Treatment for Complex Post-Traumatic Stress Disorder: A Case Report.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

Amit JagtianiPsychiatry, Burrell Behavioral Health, Springfield, USA.
Raghu GandhiPsychiatry, Abbott Northwestern Hospital, Minneapolis, USA.
Akshat BangaInternal Medicine, Sawai Man Singh Medical College, Jaipur, IND.
Jacquetta BlackerPsychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, USA.
Riecha JoshiPediatrics, Government Medical College, Kota, Kota, IND.
Bhaswanth BolluEmergency Medicine, All India Institute of Medical Sciences, New Delhi, IND.
Rahul KashyapMedicine, Drexel University College of Medicine, Philadelphia, USA.
Abbott Northwestern Hospital · USAll India Institute of Medical Sciences · INBurrell Behavioral Health · USGlobal InfoTek (United States) · USGovernment Medical College · INSMS Medical College · INUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to traumatic stress is common among children. Post-traumatic stress disorder (PTSD) is a debilitating chronic mental disorder that can develop following exposure to a traumatic event. Psychopharmacological research in pediatric PTSD is limited. There is some evidence supporting the use of alpha-2 (α

Indexed as

adolescentschildrenclonidineguanfacinepost-traumatic stress disorderα2 agonists

Identifiers

PMID38410304
PMCPMC10895561
OpenAlexW4391270115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.