Article in Anatomical record (Hoboken, N.J. : 2007), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors at 5 institutions in 2 countries.
Heather A RichbourgDepartment of Orthopedic Surgery, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-4081-1073
Marta Vidal-GarcíaAlberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-7617-7329
Katherine A BrakoraDepartment of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, Texas, USA.ORCID 0000-0002-7056-1271
Jay DevineAlberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0600-1058
Risa TakenakaDepartment of Orthopedic Surgery, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0003-2177-6759
Nathan M YoungDepartment of Orthopedic Surgery, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-3437-7493
Siew-Ging GongFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-9576-0074
Amanda NevesThe McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.
Benedikt HallgrímssonAlberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-7192-9103
Ralph S MarcucioDepartment of Orthopedic Surgery, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-0537-818X
University of California, San Francisco · USUniversity of Calgary · CAAlberta Environment and Protected Areas · CATexas A&M Health Science Center · USUniversity of Toronto · CA
Funding
The role of continuous phenotypic variation in structural defects of the faceR01DE019638 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Benedikt Hallgrimsson, Ralph S Marcucio · 2010 to 2026
$7.3M
MOLECULAR BASIS OF TISSUE INTERACTIONS THAT REGULATE CRANIOFACIAL DEVELOPMENTR01DE018234 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCUCIO, RALPH S · 2007 to 2017
$3.5M
Mechanisms of shape variation in a mouse model of craniofacial birth defectsF32DE028476 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RICHBOURG, HEATHER A · 2018 to 2020
$171k
The role of CRISPLD2 in mediating FGF8 signaling during craniofacial developmentF32DE024939 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRAKORA, KATHERINE · 2014 to 2016
$89k
Alberta Children's Hospital Research InstituteAlberta Children's Hospital Research Institute Graduate ScholarshipAlberta Children's Hospital Research Institute Postdoctoral FellowshipAlberta Innovates Postdoctoral Fellowship on Health InnovationCanada First Research Excellence Fund CFREF2022-00015Canadian Foundation for Innovation #362620CIHR Foundation Grant 159920NIDCR NIH HHS F32 DE024939NIDCR NIH HHS F32 DE028476NIDCR NIH HHS R01 DE018234NIDCR NIH HHS R01 DE019638
6 · The paper itself
Abstract
Craniosynostosis is a common yet complex birth defect, characterized by premature fusion of the cranial sutures that can be syndromic or nonsyndromic. With over 180 syndromic associations, reaching genetic diagnoses and understanding variations in underlying cellular mechanisms remains a challenge. Variants of FGFR2 are highly associated with craniosynostosis and warrant further investigation. Using the missense mutation FGFR2
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Dosage-dependent effects of FGFR2 · full record | OpenQuestion