Evidence map›Paper›PMID 38409819›Full record

ArticleThe Journal of physiology2024

Right ventricular performance during acute hypoxic exercise.

Lindsay M Forbes, Todd M Bull, Tim Lahm, Tyler Sisson, Katie O'Gean, Justin S Lawley, Kendall Hunter, Benjamin D Levine, Andrew Lovering, Robert C Roach and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Red Blood Cell Metabolic Responses during Acute Hypoxic Exercise in Healthy Adults.American journal of respiratory cell and molecular biology · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Lindsay M ForbesDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO, USA.
Todd M BullDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO, USA.
Tim LahmDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO, USA.
Tyler SissonClinical Translational Research Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Katie O'GeanClinical Translational Research Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Justin S LawleyDepartment of Sport Science, University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-2166-7966
Kendall HunterDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Benjamin D LevineDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-9064-7251
Andrew LoveringDepartment of Physiology, University of Oregon, Eugene, OR, USA.ORCID 0000-0001-7826-4290
Robert C RoachDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO, USA.
Andrew W SubudhiDepartment of Physiology, University of Colorado, Colorado Springs, CO, USA.
William K CornwellClinical Translational Research Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
University of Colorado Anschutz Medical Campus · USUniversity of Colorado Hospital · USEurac Research · ITPresbyterian Hospital · USUniversity of Colorado Colorado Springs · USUniversity of Oregon · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
S-nitrosylation signaling in asthmaP01HL158507 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI LAHM, TIM · 2021 to 2025
$12.0M
Mechanisms of Right Ventricle Adaptation to Pulmonary HypertensionR01HL144727 · NHLBI · NATIONAL JEWISH HEALTH · PI Tim Lahm · 2019 to 2026
$4.7M
Effect of Mechanical Circulatory Support on Exercise Capacity in Heart FailureK23HL132048 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CORNWELL, WILLIAM · 2016 to 2020
$819k
Hypoxia-mediated protective estrogen receptor signaling in pulmonary hypertensionI01BX002042 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Tim Lahm · 2014 to 2026
–
BLRD VA I01 BX002042NCATS NIH HHS UL1 TR002535NCATS NIH HHS UM1 TR004399NHLBI NIH HHS K23 HL132048NHLBI NIH HHS P01 HL158507NHLBI NIH HHS R01 HL144727NHLBI NIH HHS T32 HL007085NIH HHS 1K23HLi32048NIH HHS T32HL00785-48NIH HHS UL1TR002535
6 · The paper itself

Abstract

Acute hypoxia increases pulmonary arterial (PA) pressures, though its effect on right ventricular (RV) function is controversial. The objective of this study was to characterize exertional RV performance during acute hypoxia. Ten healthy participants (34 ± 10 years, 7 males) completed three visits: visits 1 and 2 included non-invasive normoxic (fraction of inspired oxygen (

Indexed as

ExerciseHypoxiaVentricular Function, RightAdultExercise TestFemaleHeart VentriclesHumansMaleOxygen Consumptionexercisehaemodynamicshypoxiaright ventricle

Identifiers

PMID38409819
PMCPMC11345882
OpenAlexW4392194574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.