Evidence map›Paper›PMID 38409600›Full record

ArticleBritish journal of cancer2024

Risk of cancer and serious disease in Danish patients with urgent referral for serious non-specific symptoms and signs of cancer in Funen 2014-2021.

Rasmus Birkholm Grønnemose, Per Syrak Hansen, Søren Worsøe Laursen, Oke Gerke, Jakob Kjellberg, Jesper Lykkegaard, Clara Thye-Rønn, Poul Flemming Høilund-Carlsen, Peter Thye-Rønn

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Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rasmus Birkholm GrønnemoseDiagnostic Centre, Svendborg Hospital, Odense University Hospital, Svendborg, Denmark. rasmus.birkholm.gronnemose@rsyd.dk.ORCID 0000-0001-6411-9981
Per Syrak HansenDiagnostic Centre, Svendborg Hospital, Odense University Hospital, Svendborg, Denmark.
Søren Worsøe LaursenThe Danish Cancer Society, Copenhagen, Denmark.ORCID 0009-0000-6108-9844
Oke GerkeDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-6335-3303
Jakob KjellbergVIVE, The Danish Centre for Social Science Research, Copenhagen, Denmark.
Jesper LykkegaardResearch Unit of General Practice, University of Southern Denmark, Odense, Denmark.
Clara Thye-RønnDiagnostic Centre, Svendborg Hospital, Odense University Hospital, Svendborg, Denmark.
Poul Flemming Høilund-CarlsenDepartment of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-7420-2367
Peter Thye-RønnDiagnostic Centre, Svendborg Hospital, Odense University Hospital, Svendborg, Denmark. peter.thye-ronn@rsyd.dk.ORCID 0000-0002-7486-8086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2011, as the first European country, Denmark introduced the non-organ-specific cancer patient pathway (CPP) for patients presenting with non-specific symptoms and signs of cancer (NSSC). The proportion of patients with cancer over time is unknown.

methodsA retrospective cohort study of all patients with a NSSC-CPP investigational course in the province of Funen to the Diagnostic Centre in Svendborg from 2014 to 2021 was performed to evaluate the proportion of patients with cancer and serious disease over time.

resultsA total of 6698 patients were referred to the NSSC-CPP of which 20.2% had cancer. While the crude referral rate increased from 114 per 100,000 people in 2014 and stabilised to around 214 in 2017-2021, the cancer detection rate of the total yearly new cancers in Funen diagnosed through the NSSC-CPP in DC Svendborg increased from 3 to 6%.

conclusionsWith now high and stable conversion and crude referral rates, the NSSC-CPP is one of the largest CPPs in Denmark as measured by the number of new cancer cases found. Similar urgent referral programmes in other countries might fill an unmet medical need for patients presenting with serious non-specific symptoms and signs of cancer in general practice.

Indexed as

Early Detection of CancerNeoplasmsDenmarkHumansReferral and ConsultationRetrospective Studies

Identifiers

PMID38409600
PMCPMC11014902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.