Evidence map›Paper›PMID 38409473›Full record

ArticleScientific reports2024

Cerebral white matter hyperintensities indicate severity and progression of coronary artery calcification.

Markus Kneihsl, Thomas Gattringer, Edith Hofer, Peter P Rainer, Gerhard Ranner, Simon Fandler-Höfler, Melanie Haidegger, Sabine Perl, Christian Enzinger, Reinhold Schmidt

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Markus KneihslDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Thomas GattringerDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria. thomas.gattringer@medunigraz.at.
Edith HoferDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Peter P RainerDivision of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Gerhard RannerCT and MR Imaging Center Geidorf, Graz, Austria.
Simon Fandler-HöflerDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Melanie HaideggerDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Sabine PerlDivision of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Christian EnzingerDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Reinhold SchmidtDepartment of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Medical University of Graz · ATBioTechMed-Graz · ATImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral white matter hyperintensities (WMH) have been associated with subclinical atherosclerosis including coronary artery calcification (CAC). However, previous studies on this association are limited by only cross-sectional analysis. We aimed to explore the relationship between WMH and CAC in elderly individuals both cross-sectionally and longitudinally. The study population consisted of elderly stroke- and dementia-free participants from the community-based Austrian Stroke Prevention Family Study (ASPFS). WMH volume and CAC levels (via Agatston score) were analyzed at baseline and after a 6-year follow-up period. Of 324 study participants (median age: 68 years), 115 underwent follow-up. Baseline WMH volume (median: 4.1 cm

Indexed as

Coronary Artery DiseaseStrokeVascular CalcificationWhite MatterAgedCross-Sectional StudiesDisease ProgressionHumansMagnetic Resonance ImagingRisk FactorsAgingCerebral small vessel diseaseCoronary artery calcificationWhite matter hyperintensities

Identifiers

PMID38409473
PMCPMC10897190
OpenAlexW4392169434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.