Evidence map›Paper›PMID 38408941›Full record

ArticleBMC public health2024

Experience and impact of stigma in people with chronic hepatitis B: a qualitative study in Asia, Europe, and the United States.

Mondher Toumi, Jack Wallace, Chari Cohen, Chris Marshall, Helen Kitchen, Jake Macey, Hannah Pegram, Ashley F Slagle, Robert G Gish, Qin Ning and 20 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Observational
  5. Review
  6. The Silent Burden of Hepatitis B-Related Stigma.Journal of viral hepatitis · 2026
    Article
  7. [APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  8. Article
  9. Traveling with chronic viral hepatitis.Tropical diseases, travel medicine and vaccines · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Time for a globally unified chronic HBV terminology?JHEP reports : innovation in hepatology · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 15 institutions in 9 countries.

Mondher ToumiAix-Marseille University, Jardin du Pharo, 58 bd Charles Livon, Marseille, 13284 Cedex 07, France. Mondher.Toumi@emaud.eu.
Jack WallaceBurnet Institute, 85 Commercial Rd, Melbourne, VIC, 3004, Australia.
Chari CohenHepatitis B Foundation, 3805 Old Easton Rd, Doylestown, PA, 18902, USA.
Chris MarshallClarivate (formerly DRG Abacus), 70 St Mary Axe, London, EC3A 8BE, UK.
Helen KitchenClarivate (formerly DRG Abacus), 70 St Mary Axe, London, EC3A 8BE, UK.
Jake MaceyClarivate (formerly DRG Abacus), 70 St Mary Axe, London, EC3A 8BE, UK.
Hannah PegramClarivate (formerly DRG Abacus), 70 St Mary Axe, London, EC3A 8BE, UK.
Ashley F SlagleAspen Consulting, LLC, 625 S Lincoln Ave #101, Steamboat Springs, CO, 80487, USA.
Robert G GishHepatitis B Foundation, 3805 Old Easton Rd, Doylestown, PA, 18902, USA.
Qin NingTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie Fang Avenue, Hankou, Wuhan, 430030, China.
Hiroshi YatsuhashiNational Hospital Organization (NHO) Nagasaki Medical Center, 2-1001-1, Kubara, Omura, Nagasaki, 856-8562, Japan.
Markus CornbergHannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Maurizia BrunettoUniversity Hospital of Pisa, Lungarno Pacinotti 43, Pisa, 56126, Italy.
Florian van BömmelDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, Liebigstrasse 20, 04103, Leipzig, Germany.
Qing XieShanghai Jiao Tong University School of Medicine, Ruijin Hospital, 227 South Chongqing Road, Shanghai, 20025, China.
Dee LeeInno Community Development Organisation, Room 208, Dengzheng Business Center, #57, Dengzhengnan Rd, Yuexiu District, Guangzhou, Guangdong, China.
Noriyuki HabukaJanssen Pharmaceutical K.K, 3-5-2 Nishi-kanda, Chiyoda-ku, Tokyo, 101-0065, Japan.
Urbano SbarigiaJanssen Pharmaceutica NV, Turnhoutseweg 30, Beerse, B-2340, Belgium.
Maria Beumont-MauvielJanssen Research & Development, LLC, 1125 Trenton Harbourton Rd, Titusville, NJ, 08560, USA.
Angelina Villasis KeeverJanssen Research & Development, 1400 McKeon Road, Spring House, PA, 19002, USA.
Yasushi TakahashiJanssen Pharmaceutical K.K, 3-5-2 Nishi-kanda, Chiyoda-ku, Tokyo, 101-0065, Japan.
Yiwei LuJanssen China, 14F, Tower 3, China Central Place, No.77, Jian Guo Road, Chaoyang District, Beijing, 100025, China.
Ao LiuJanssen China, 14F, Tower 3, China Central Place, No.77, Jian Guo Road, Chaoyang District, Beijing, 100025, China.
Qiaoqiao ChenJanssen China, 14F, Tower 3, China Central Place, No.77, Jian Guo Road, Chaoyang District, Beijing, 100025, China.
Tetsuro ItoJanssen Health Economics & Market Access (EMEA), 50-100 Holmers Farm Way, High Wycombe, Buckinghamshire, HP12 4EG, UK.
Olaf RadunzJanssen Germany, Johnson-u.-Johnson-Platz 1, 41470, Neuss, Nordrhein-Westfalen, Germany.
Anna PugginaJanssen Italy, Via Michelangelo Buonarroti, 23, Cologno Monzese, 20093, Italy.
Gudrun HilgardJanssen Germany, Johnson-u.-Johnson-Platz 1, 41470, Neuss, Nordrhein-Westfalen, Germany.
Eric K H ChanJanssen Global Services, LLC, 1000 US 202, Raritan, NJ, 08869, USA. echan15@ITS.JNJ.com.
Su WangHepatitis B Foundation, 3805 Old Easton Rd, Doylestown, PA, 18902, USA.
Janssen (United States) · USHepatitis B Foundation · USJanssen (Germany) · DEAix-Marseille Université · FRAzienda Ospedaliera Universitaria Pisana · ITBurnet Institute · AUJanssen (Belgium) · BEJanssen (Italy) · ITJanssen (United Kingdom) · GBLeipzig University · DEMedizinische Hochschule Hannover · DENagasaki Medical Center · JPRuijin Hospital · CNSaint Barnabas Medical Center · USTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with chronic hepatitis B (CHB) commonly experience social and self-stigma. This study sought to understand the impacts of CHB-related stigma and a functional cure on stigma.

methodsAdults with CHB with a wide range of age and education were recruited from 5 countries and participated in 90-minute qualitative, semi-structured interviews to explore concepts related to CHB-associated stigma and its impact. Participants answered open-ended concept-elicitation questions regarding their experience of social and self-stigma, and the potential impact of reduced CHB-related stigma.

resultsSixty-three participants aged 25 to 71 years (15 from the United States and 12 each from China, Germany, Italy, and Japan) reported emotional, lifestyle, and social impacts of living with CHB, including prejudice, marginalization, and negative relationship and work experiences. Self-stigma led to low self-esteem, concealment of CHB status, and social withdrawal. Most participants stated a functional cure for hepatitis B would reduce self-stigma.

conclusionsCHB-related social and self-stigma are widely prevalent and affect many aspects of life. A functional cure for hepatitis B may reduce social and self-stigma and substantially improve the health-related quality of life of people with CHB. Incorporating stigma into guidelines along with infectivity considerations may broaden the patient groups who should receive treatment.

Indexed as

Hepatitis BHepatitis B, ChronicAdultAsiaEuropeHumansQuality of LifeSocial StigmaUnited StatesChronic Hepatitis BFunctional cureHepatitis B virusQualitative researchSelf-stigmaSocial impact

Identifiers

PMID38408941
PMCPMC10895774
OpenAlexW4392165830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.