Evidence map›Paper›PMID 38408413›Full record

ArticleInternational journal of pediatric otorhinolaryngology2024

Long-range optical coherence tomography of pediatric airway during drug induced sleep endoscopy: A preliminary report.

Khodayar Goshtasbi, Erica Su, Joseph C Jing, Theodore V Nguyen, Ellen M Hong, Katelyn D Dilley, Gurpreet S Ahuja, Zhongping Chen, Brian J F Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khodayar GoshtasbiDepartment of Otolaryngology-Head and Neck Surgery, University of California Irvine, Irvine, CA, USA; Beckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Erica SuBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Joseph C JingBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Theodore V NguyenBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Ellen M HongBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Katelyn D DilleyBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Gurpreet S AhujaDivision of Pediatric Otolaryngology, Children's Hospital of Orange County, Orange, CA, USA.
Zhongping ChenBeckman Laser Institute, University of California Irvine, Irvine, CA, USA; School of Biomedical Engineering, University of California Irvine, Irvine, CA, USA.
Brian J F WongDepartment of Otolaryngology-Head and Neck Surgery, University of California Irvine, Irvine, CA, USA; Beckman Laser Institute, University of California Irvine, Irvine, CA, USA; School of Biomedical Engineering, University of California Irvine, Irvine, CA, USA. Electronic address: bjwong@uci.edu.

Funding

Phase resolved ARF optical coherence elastography for intravascular imagingR01HL125084 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ZHOU, QIFA · 2014 to 2023
$5.6M
Combined OCT/US/PAT system for intravascular ImagingR01HL127271 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, PATEL, PRANAV · 2015 to 2018
$2.7M
In vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging TechnologyR01EB030024 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, WONG, BRIAN · 2020 to 2024
$2.3M
Continuous Monitoring and Management of Vaginal Health via Multifunctional OCT/OCTA EndoscopyR01EB030558 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, LANE, FELICIA LUCIA · 2021 to 2021
$1.9M
NHLBI NIH HHS R01 HL125084NHLBI NIH HHS R01 HL127271NIBIB NIH HHS R01 EB030024NIBIB NIH HHS R01 EB030558
6 · The paper itself

Abstract

objectiveDrug induced sleep endoscopy (DISE) is often performed for pediatric obstructive sleep apnea (OSA) when initial diagnostic studies do not provide adequate information for therapy. However, DISE scoring is subjective and with limitations. This proof-of-concept study demonstrates the use of a novel long-range optical coherence tomography (LR-OCT) system during DISE of two pediatric patients.

methodsLR-OCT was used to visualize the airway of pediatric patients during DISE. At the conclusion of DISE, the OCT probe was guided in the airway under endoscopic visual guidance, and cross-sectional images were acquired at the four VOTE locations. Data processing involved image resizing and alignment, followed by rendering of three-dimensional (3D) volumetric models of the airways.

resultsTwo patients were included in this study. Patient one had 18.4%, 20.9%, 72.3%, and 97.3% maximal obstruction at velum, oropharynx, tongue base, and epiglottis, while patient two had 40.2%, 41.4%, 8.0%, and 17.5% maximal obstruction at these regions, respectively. Three-dimensional reconstructions of patients' airways were also constructed from the OCT images.

conclusionThis proof-of-concept study demonstrates the successful evaluation of pediatric airway during DISE using LR-OCT, which accurately identified sites and degrees of obstruction with respective 3D airway reconstruction.

Indexed as

Airway ObstructionSleep Apnea, ObstructiveChildEndoscopyHumansPolysomnographySleepTomography, Optical Coherence

Identifiers

PMID38408413
PMCPMC11956761

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.