Evidence map›Paper›PMID 38407369›Full record

ArticleThe British journal of radiology2024

Geometric distortion caused by metallic femoral head prosthesis in prostate cancer imaging on an MR Linac: in-vivo measurements of spatial deformation.

Lisa McDaid, Abigael Clough, Rebecca K Benson, Claire Nelder, John McMahon, Steven Jackson, Marianne Aznar, Ananya C Choudhury, Marcel van Herk, Cynthia L Eccles

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lisa McDaidDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.ORCID 0000-0002-2473-8734
Abigael CloughDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Rebecca K BensonDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Claire NelderDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
John McMahonDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Steven JacksonChristie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, M20 4BX, United Kingdom.
Marianne AznarManchester Academic Health Science Centre, Radiotherapy Related Research, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, M20 4BX, United Kingdom.ORCID 0000-0001-6452-0310
Ananya C ChoudhuryDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Marcel van HerkManchester Academic Health Science Centre, Radiotherapy Related Research, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, M20 4BX, United Kingdom.ORCID 0000-0001-6448-898X
Cynthia L EcclesDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.ORCID 0000-0002-5445-5428
The Christie NHS Foundation Trust · GBManchester Academic Health Science Centre · GB

Funding

Cancer Research UK RadNet Manchester C1994/A28701Department of Health and Social CareEngineering and Physical Sciences Research Council EP/T028017/1Manchester Biomedical Research Centre NIHR203308NIHR
6 · The paper itself

Abstract

objectivesMetallic implants cause artefacts and distortion on MRI. To ensure accurate dose delivery and plan adaptation on an MR Linac, there is a need to evaluate distortion caused.

methodsParticipants were imaged on an MR Linac (Elekta Unity, Elekta AB Stockholm). Three sequences were evaluated. Two vendor supplied (T2W TSE 3D), and one T2W TSE 3D optimized to reduce metal artefact distortions. Images were rigidly registered to CT images by a single observer, using bony anatomy. Three coronal and three axial images were selected, and six paired, adjacent, bony landmarks were identified on each slice. Images bisecting treatment isocentre were included. Difference between landmark coordinates was taken to be measure of distortion.

resultsFive observers participated. Thirty six pairs of bony landmarks were identified. Median difference in position of landmarks was ≤3 mm (range 0.3-4.4 mm). One-way analysis of variance (ANOVA) between observer means showed no significant variation between sequences or patients (P = 1.26 in plane, P = 0.11 through plane). Interobserver intra class correlation (ICC) was 0.70 in-plane and 0.78 through-plane. Intra-observer ICC for three observers was 0.76, 0.81, 0.83, showing moderate to good reliability on this small cohort.

conclusionsThis in-vivo feasibility study suggests distortion due to metallic hip prosthesis is not an obstacle for pelvic radiotherapy on an MR Linac. Research on the impact on plan quality is warranted. ADVANCES IN KNOWLEDGE: This work supports feasibility of treating patients with metallic hip prosthesis on an MR Linac.

Indexed as

Hip ProsthesisProstatic NeoplasmsHumansMagnetic Resonance ImagingMaleParticle AcceleratorsPhantoms, ImagingRadiotherapy Planning, Computer-AssistedReproducibility of Resultsgeometric distortionmetallic prosthesisMR-guided radiotherapyMR Linacprostate radiotherapy

Identifiers

PMID38407369
PMCPMC11027238
OpenAlexW4392157508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.