Evidence map›Paper›PMID 38407331›Full record

ArticleNeurourology and urodynamics2024

Characterizing the spectrum of bladder health and lower urinary tract symptoms among men: Results from the CARDIA study.

Alayne D Markland, Gerhard Hellemann, Liang Shan, Sonya S Brady, Jared D Huling, Pamela J Schreiner, Stephen Sidney, Stephen K Van Den Eeden, Cora E Lewis

Open access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alayne D MarklandDepartment of Veterans Affairs, Birmingham/Atlanta Geriatric Research, Education, and Clinical Center (GRECC), Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0002-6567-6744
Gerhard HellemannSchool of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Liang ShanSchool of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Sonya S BradySchool of Public Health, Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, Minnesota, USA.ORCID http://orcid.org/0000-0001-8660-9308
Jared D HulingSchool of Public Health, Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Pamela J SchreinerSchool of Public Health, Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Stephen SidneyDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Stephen K Van Den EedenDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Cora E LewisSchool of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USUniversity of Minnesota · USKaiser Permanente · US

Funding

CARDIA-PLUS: A Life Course Investigation of Biopsychosocial Pathways to Bladder Health and Lower Urinary Tract SymptomsR01DK125274 · NIDDK · UNIVERSITY OF MINNESOTA · PI BRADY, SONYA S, MARKLAND, ALAYNE DENISE · 2021 to 2024
$2.5M
Research and Mentoring Program in Improving Access to Incontinence Care for Older AdultsK24AG073586 · NIA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Alayne Denise Markland · 2022 to 2026
$619k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INIA NIH HHS K24 AG073586NIDDK NIH HHS R01 DK125274NIH HHS
6 · The paper itself

Abstract

objectivesTo operationalize a new definition for bladder health, we examined the distribution and impact of lower urinary tract symptoms (LUTS), along with risk factors, among men in the Coronary Artery Risk Development in Young Adults (CARDIA) study.

methodsLUTS were defined by American Urologic Association Symptom Index (AUASI) scores and impact on quality of life (QoL). Separate questions assessed urinary incontinence (UI) and postvoid dribbling. We performed cluster analyses using AUASI scores, with and without urine incontinence and postvoid dribbling, and impact collected in 2010-11. We performed analyses to evaluate sociodemographic and cardiovascular risk factors between clusters.

resultsAmong CARDIA men (mean age: 50.0, SD = 3.6; range: 42-56 years) with complete LUTS data (n = 929), we identified and compared four clusters: men who reported no or very mild symptoms and no impact on well-being (bladder health, n = 696, 75%), men with moderate symptoms and moderate impact on well-being (moderate symptoms/impact, n = 84, 9%), men with high symptoms and high impact on well-being (severe symptoms/impact, n = 117, 13%), and a separate group that reported moderate symptoms and UI with a high impact on well-being (UI + moderate symptoms/severe impact, n = 32, 3%). Exploration of the groupings showed a large percentage of postvoid dribbling across groups (overall 69%). Sociodemographic and cardiovascular risk factors were not associated with symptom/impact groups.

conclusionsBladder health clustered into four categories. A majority of middle-aged men in the community showed no or mild bladder symptoms without impact on QoL. Postvoid dribbling is pervasive but did not cluster with a specific LUTS or impact category.

Indexed as

Lower Urinary Tract SymptomsUrinary IncontinenceCoronary VesselsHumansMaleMiddle AgedQuality of LifeUrinary BladderYoung Adultbladder healthcluster analysishealth‐related quality of lifelower urinary tract symptomsmen

Identifiers

PMID38407331
PMCPMC11031325
OpenAlexW4392166595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.