Evidence map›Paper›PMID 38406806›Full record

SynthesisFrontiers in oncology2024

Frailty worsens long-term survival in patients with colorectal cancer: a systematic review and meta-analysis.

Jiangxue Han, Qin Zhang, Jiarong Lan, Fang Yu, Jie Liu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Development and validation of a Chinese version of the frailty risk perception questionnaire for older adults with colorectal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  11. Clinical Frailty Scale predicts overall survival after colon cancer surgery in people aged 80 years and older: A prospective multicentre observational study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Observational
  12. Observational
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiangxue HanOncology Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, China.
Qin Zhang *Oncology Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, China.
Jiarong Lan *School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Fang YuDepartment of Pathology, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, China.
Jie LiuInstitute of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) is the 3 Methods: This PROSPERO registered review examined the databases of PubMed, Embase, and Web of Science till 4 Results: 15 studies with 45288 patients were included. 6573 patients (14.5%) were frail. Meta-analysis demonstrated that frailty was associated with statistically significant poor overall survival (OS) (HR: 2.11 95% CI: 1.44, 3.08 I Conclusion: Our results show that frail CRC patients have poor OS and DFS as compared to non-frail patients. Variations in frailty measurement tools and high inter-study heterogeneity are major limitations of the review. Systematic review registration: https://www.crd.york.ac.uk/prospero/, PROSPERO, CRD42023450586.

Indexed as

carcinomafrailgeriatricmortalityrecurrence

Identifiers

PMID38406806
PMCPMC10889110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.