Evidence map›Paper›PMID 38406801›Full record

ArticleFrontiers in oncology2024

Afsaneh Barzi, Caroline M Weipert, Carin R Espenschied, Victoria M Raymond, Andrea Wang-Gillam, Mohammad Amin Nezami, Eva J Gordon, Daruka Mahadevan, Kabir Mody

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Afsaneh BarziDepartment of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA, United States.
Caroline M WeipertGuardant Health, Redwood City, CA, United States.
Carin R EspenschiedGuardant Health, Redwood City, CA, United States.
Victoria M RaymondGuardant Health, Redwood City, CA, United States.
Andrea Wang-GillamDivision of Oncology, Siteman Cancer Center, St. Louis, MO, United States.
Mohammad Amin NezamiOrange Coast Medical Center of Hope, Newport Beach, CA, United States.
Eva J GordonPrivate Health Management, Inc., Los Angeles, CA, United States.
Daruka MahadevanDivision of Hematology and Oncology, Department of Medicine, University of Texas Health, San Antonio, San Antonio, TX, United States.
Kabir ModyDivision of Hematology-Oncology, Department of Medicine, Mayo Clinic, Jacksonville, FL, United States.
Guardant (United States) · USCity Of Hope National Medical Center · USMayo Clinic in Florida · USOrange Coast Memorial Medical Center · USThe University of Texas Health Science Center at San Antonio · USUniversity Hospitals Seidman Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Despite accumulating data regarding the genomic landscape of pancreatic ductal adenocarcinoma (PDAC), olaparib is the only biomarker-driven FDA-approved targeted therapy with a PDAC-specific approval. Treating Methods: De-identified molecular test results for all patients with pancreatic cancer who received clinical cell-free circulating DNA analysis (Guardant360) between 06/2014 and 01/2018 were analyzed. Cell-free circulating DNA analysis included next-generation sequencing of up to 73 genes, including select small insertion/deletions, copy number amplifications, and fusions. Results: Of 1,791 patients with pancreatic adenocarcinoma, 36 (2.0%) had an Conclusion: Our case series illustrates that certain patients with

Indexed as

ctDNAERBB2HER2 amplificationliquid biopsypancreatic cancer

Identifiers

PMID38406801
PMCPMC10885695
OpenAlexW4391650511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.