Evidence map›Paper›PMID 38406637›Full record

ArticleToxicology research2024

In-vitro and preclinical testing of

Ankit Negi, Tulasi Pasam, Syed Muhammad Farqadain, Y Mahalaxmi, Manoj P Dandekar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Oral toxicity evaluation ofToxicology research · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ankit NegiDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), NH 9, Balanagar Main Rd, Kukatpally Industrial Estate, Balanagar, Hyderabad, Telangana 500037, India.
Tulasi PasamDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), NH 9, Balanagar Main Rd, Kukatpally Industrial Estate, Balanagar, Hyderabad, Telangana 500037, India.
Syed Muhammad FarqadainUnique Biotech Limited, Centre for Research and Development, Hyderabad, Telangana, 500 101, India.
Y MahalaxmiUnique Biotech Limited, Centre for Research and Development, Hyderabad, Telangana, 500 101, India.
Manoj P DandekarDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), NH 9, Balanagar Main Rd, Kukatpally Industrial Estate, Balanagar, Hyderabad, Telangana 500037, India.ORCID https://orcid.org/0000-0002-5412-7547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Probiotics made from Materials and methods: According to Organization for Economic Co-operation and Development (OECD) 423 and 407 requirements, a preclinical investigation was conducted in male and female Sprague-Dawley rats. Acute toxicity was examined following a single peroral (PO) administration of 5,000 mg/kg body weight (bw) i.e. equivalent to 500 billion colony-forming units (CFU) per kg bw. Single administration of Results: Incubation of Conclusion:

Indexed as

28-day repeated dose toxicityacute toxicityBacillus subtilis UBBS-14OECD guidelinesprobioticssafety

Identifiers

PMID38406637
PMCPMC10891425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.