Evidence map›Paper›PMID 38406581›Full record

ArticleSAGE open medicine2024

Intravenous versus intramuscular oxytocin injection for preventing uterine atonic primary postpartum haemorrhage in third stage of labour: A double-blind randomised controlled trial.

Emmanuel Ikechukwu Okaforcha, George Uchenna Eleje, Joseph Ifeanyichukwu Ikechebelu, Chukwuemeka Okwudili Ezeama, Emeka Philip Igbodike, Emmanuel Onyebuchi Ugwu, Boniface Chukwuneme Okpala, Ikechukwu Innocent Mbachu, Osita Samuel Umeononihu, Chukwudi Anthony Ogabido and 7 more

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Emmanuel Ikechukwu OkaforchaDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
George Uchenna ElejeDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.ORCID https://orcid.org/0000-0002-0390-2152
Joseph Ifeanyichukwu IkechebeluDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.ORCID https://orcid.org/0000-0003-2515-8464
Chukwuemeka Okwudili EzeamaDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Emeka Philip IgbodikeDepartment of Obstetrics and Gynaecology, Havana Hospital, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-4698-6226
Emmanuel Onyebuchi UgwuDepartment of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Nigeria.ORCID https://orcid.org/0000-0002-3342-434X
Boniface Chukwuneme OkpalaDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.ORCID https://orcid.org/0000-0003-1693-373X
Ikechukwu Innocent MbachuDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Osita Samuel UmeononihuDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Chukwudi Anthony OgabidoDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Daniel Nnaemeka OnwusuluDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Charlotte Blanche OguejioforDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Chidinma Charity OkaforDepartment of Psychiatry, Leicestershire Partnership NHS Trust, Leicester, UK.
Chinedu Lawrence OlisaDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
David Chibuike IkwukaDepartment of Medical Physiology, College of Medicine and Health Sciences, University of Rwanda, Huye, Rwanda.
Ifeanyichukwu Jude OforDepartment of Obstetrics and Gynaecology, ESUT College of Medicine, Parklane, Nigeria.
Chigozie Geoffrey OkaforDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.ORCID https://orcid.org/0000-0003-4458-8216
Nnamdi Azikiwe University · NGNnamdi Azikiwe University Teaching Hospital · NGUniversity of Rwanda · RWLagos University Teaching Hospital · NGUniversity of Nigeria Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To compare the efficacy and safety of intravenous and intramuscular oxytocin in preventing atonic primary postpartum haemorrhage in the third stage of labour. Methods: A double-blind randomised clinical study on consenting women without risk factors for primary postpartum haemorrhage in labour at term. Two hundred and thirty-two women were randomly allotted into intravenous ( Results: The baseline socio-demographic and clinical characteristics were similar between the two groups ( Conclusion: Although oxytocin in both study groups showed similar efficacy in terms of preventing atonic primary postpartum haemorrhage, participants who received intravenous oxytocin were more likely to require additional uterotonics to reduce their likelihood of having an atonic primary postpartum haemorrhage. However, both routes have similar side effect profiles.

Indexed as

intramuscular routeIntravenous routeoxytocinprimary postpartum haemorrhagethird stage of labouruterine atony

Identifiers

PMID38406581
PMCPMC10894536
OpenAlexW4392113400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.