Evidence map›Paper›PMID 38406525›Full record

ArticleEJHaem2024

Primary renal leukaemia in a young adult male as an extramedullary presentation of T cell acute lymphoblastic leukaemia.

Punit Jain, Poonam Jain, Robert S Ohgami, Veena Pawar, Kunal Sehgal, Pradnya Chaudhari, Ravindra Nikalji, Tejinder Singh, Vipin Khandelwal, Sanjay Khare and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Punit JainHaematology Oncology and Stem Cell Transplant Unit Apollo Hospitals Navi Mumbai India.ORCID https://orcid.org/0000-0003-3711-1014
Poonam JainHelix Genetic and Pathology Laboratory Mumbai India.
Robert S OhgamiHematopathology University of Utah Salt Lake City Utah USA.
Veena PawarHematopathology Apollo Hospitals Navi Mumbai India.
Kunal SehgalHematopathology Sehgal Path Lab Private Limited Mumbai India.
Pradnya ChaudhariHematopathology Apollo Hospitals Navi Mumbai India.
Ravindra NikaljiNephrology Apollo Hospitals Navi Mumbai India.
Tejinder SinghHaematology Oncology and Stem Cell Transplant Unit Apollo Hospitals Navi Mumbai India.
Vipin KhandelwalHaematology Oncology and Stem Cell Transplant Unit Apollo Hospitals Navi Mumbai India.
Sanjay KhareGeneral Medicine Apollo Hospitals Navi Mumbai India.
Vaishali LokhandeGeneral Medicine Apollo Hospitals Navi Mumbai India.
Ashwathy HaridasNephrology Apollo Hospitals Navi Mumbai India.
Laxman JessaniInfectious Disease Apollo Hospitals Navi Mumbai India.
Kanika KhandelwalHaematology Oncology and Stem Cell Transplant Unit Apollo Hospitals Navi Mumbai India.
Apollo Hospitals · INApollo Hospitals · INUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary renal involvement by T lymphoblasts is rare among adults with T acute lymphoblastic leukaemia. We report a 28-year-old man presenting with acute renal failure due to infiltration by T lymphoblasts and his response to paediatric-inspired modified BFM-90 protocol. The patient achieved an initial complete remission (CR) but developed central nervous system relapse. He achieved CR2 with cranial irradiation and intrathecal chemotherapy. He underwent a haploidentical transplant in CR2 and remains in remission post-transplant day 330. An early kidney biopsy helped confirm the diagnosis. Such presentations remain responsive to modified BFM-90. An early allotransplant in CR2 remains the standard of care.

Indexed as

acute renal failure in T‐ALLextramedullary manifestations in T‐ALLModified BFM‐90 protocolT cell acute lymphoblastic leukaemia

Identifiers

PMID38406525
PMCPMC10887257
OpenAlexW4388732630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.