Evidence map›Paper›PMID 38406504›Full record

ArticleEJHaem2024

Efficacy and manageable safety of tagraxofusp in blastic plasmacytoid dendritic cell neoplasm: a case series of pediatric and adolescent/young adult patients.

Naveen Pemmaraju, Branko Cuglievan, Joseph Lasky, Albert Kheradpour, Nobuko Hijiya, Anthony S Stein, Soheil Meshinchi, Craig A Mullen, Emanuele Angelucci, Luciana Vinti and 2 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. BPDCN: state of the art.Hematology. American Society of Hematology. Education Program · 2024
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Naveen PemmarajuDepartment of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA.ORCID https://orcid.org/0000-0002-1670-6513
Branko CuglievanDepartment of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA.
Joseph LaskyCure 4 The Kids Foundation Las Vegas Nevada USA.
Albert KheradpourDepartment of Pediatric Hematology and Oncology Loma Linda University Children's Hospital Loma Linda California USA.
Nobuko HijiyaDivision of Pediatric Oncology, Hematology, and Stem Cell Transplantation Columbia University Irving Medical Center New York New York USA.
Anthony S SteinDepartment of Hematology and Hematopoietic Cell Transplantation City of Hope National Medical Center Duarte California USA.
Soheil MeshinchiDepartment of Pediatrics University of Washington School of Medicine Seattle Washington USA.
Craig A MullenDivision of Pediatric Hematology/Oncology Department of Pediatrics Golisano Children's Hospital University of Rochester Rochester New York USA.
Emanuele AngelucciHematology and Cellular Therapy Unit, IRCCS Ospedale Policlinico San Martino Genova Italy.
Luciana VintiDepartment of Paediatric Haematology/Oncology, Cell and Gene Therapy Bambino Gesù Children's Hospital, IRCCS Rome Italy.
Tariq I MughalDivision of Hematology-Oncology Tufts University Medical School Boston Massachusetts USA.
Anna B PawlowskaDepartment of Pediatrics City of Hope National Medical Center Duarte California USA.ORCID https://orcid.org/0000-0001-9466-6396
City Of Hope National Medical Center · USThe University of Texas MD Anderson Cancer Center · USBambino Gesù Children's Hospital · ITColumbia University Irving Medical Center · USCure 4 The Kids Foundation · USGolisano Children's Hospital · USLoma Linda University Children's Hospital · USOspedale Policlinico San Martino · ITTufts University · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) predominantly occurs in adults ≥60 years old; 10-20% of cases are pediatric or adolescent/young adult (AYA) patients. Tagraxofusp (TAG, Elzonris

Indexed as

AYA BPDCNCD123pediatric BPDCNplasmacytoid dendritic cellstagraxofusp

Identifiers

PMID38406504
PMCPMC10887247
OpenAlexW4391922352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.