Evidence map›Paper›PMID 38405972›Full record

ArticlebioRxiv : the preprint server for biology2024

A nociceptive amygdala-striatal pathway for chronic pain aversion.

Jessica A Wojick, Alekh Paranjapye, Juliann K Chiu, Malaika Mahmood, Corinna Oswell, Blake A Kimmey, Lisa M Wooldridge, Nora M McCall, Alan Han, Lindsay L Ejoh and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jessica A WojickDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-0530-5482
Alekh ParanjapyeDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Juliann K ChiuDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Malaika MahmoodDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Corinna OswellDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Blake A KimmeyDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lisa M WooldridgeDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nora M McCallDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alan HanDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lindsay L EjohDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Samar Nasser ChehimiDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Richard C CristDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Benjamin C ReinerDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Erica KorbDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gregory CorderDept. of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · US

Funding

Translational Research Training Program in Environmental Health SciencesT32ES019851 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Kara A Bernstein, Trevor M Penning · 2012 to 2026
$6.0M
Harnessing cortical neuromodulation to disrupt pain perceptionDP2GM140923 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI CORDER, GREGORY · 2020 to 2022
$2.6M
The epigenetic encoding of learning and memoryDP2MH129985 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI KORB, ERICA MEGAN · 2021 to 2024
$2.4M
Deconstructing the network mechanisms of chronic pain and reward in the amygdalaR00DA043609 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI CORDER, GREGORY · 2019 to 2021
$744k
Cell-specific epigenetic and transcriptomic signatures of impulsivity and its regulation by stress in the nucleus accumbensR21DA055846 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI BANGASSER, DEBRA A, REINER, BENJAMIN CHARLES · 2023 to 2024
$469k
Single-nucleus transcriptomics in rat striatum following morphine administration and withdrawalR21DA057458 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI CRIST, RICHARD C., SCHMIDT, HEATH D · 2023 to 2024
$447k
Investigation of nociceptive endogenous opioid dynamics in the periaqueductal grayF32DA055458 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI KIMMEY, BLAKE · 2022 to 2024
$226k
Impact of fentanyl dependence on a parabrachio-amygdalar opioid circuitF31DA057795 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI WOOLDRIDGE, LISA · 2023 to 2025
$122k
Modulating pain through cortical endogenous opioid circuitsF32DA053099 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI MCCALL, NORA · 2021 to 2022
$107k
Functional characterization of an amygdala to accumbens nociceptive circuitF31NS125927 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI WOJICK, JESSICA ANNE · 2022 to 2024
$104k
Endogenous opioid modulation of cortical pain circuits.F31DA062445 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI Corinna Oswell · 2025 to 2026
$100k
NIDA NIH HHS F31 DA057795NIDA NIH HHS F31 DA062445NIDA NIH HHS F32 DA053099NIDA NIH HHS F32 DA055458NIDA NIH HHS R00 DA043609NIDA NIH HHS R21 DA055846NIDA NIH HHS R21 DA057458NIEHS NIH HHS T32 ES019851NIGMS NIH HHS DP2 GM140923NIMH NIH HHS DP2 MH129985NINDS NIH HHS F31 NS125927
6 · The paper itself

Abstract

The basolateral amygdala (BLA) is essential for assigning positive or negative valence to sensory stimuli. Noxious stimuli that cause pain are encoded by an ensemble of

Identifiers

PMID38405972
PMCPMC10888915
OpenAlexW4391799649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.