Evidence map›Paper›PMID 38405898›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Gemykibivirus detection in acute encephalitis patients from Nepal.

Eans Tara Tuladhar, Smita Shrestha, Susan Vernon, Lindsay Droit, Kathie A Mihindukulasuriya, Mamta Tamang, Lata Karki, Annie Elong Ngono, Bimlesh Jha, Bal Krishna Awal and 5 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Eans Tara TuladharTribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.ORCID 0000-0001-5705-3953
Smita ShresthaTribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.ORCID 0009-0003-1885-3159
Susan VernonWashington University in St. Louis, Missouri, United States.
Lindsay DroitWashington University in St. Louis, Missouri, United States.
Kathie A MihindukulasuriyaWashington University in St. Louis, Missouri, United States.
Mamta TamangTribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.
Lata KarkiTribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.
Annie Elong NgonoLa Jolla Institute for Immunology, California, United States.
Bimlesh JhaNational Public Health Laboratory, Kathmandu, Nepal.
Bal Krishna AwalNational Public Health Laboratory, Kathmandu, Nepal.
Bimal Sharma ChaliseSukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal.
Runa JhaNational Public Health Laboratory, Kathmandu, Nepal.
Sujan ShrestaLa Jolla Institute for Immunology, California, United States.
David WangWashington University in St. Louis, Missouri, United States.ORCID 0000-0002-0827-196X
Krishna Das ManandharTribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.ORCID 0000-0002-6798-4935

Funding

Emerging infections: surveillance, epidemiology and pathogenesisU01AI151810 · NIAID · WASHINGTON UNIVERSITY · PI Adrianus CM Boon, DAVID WANG · 2020 to 2026
$10.0M
NIAID NIH HHS U01 AI151810
6 · The paper itself

Abstract

Acute Encephalitis Syndrome (AES) causes significant morbidity and mortality worldwide. In Nepal, Japanese encephalitis virus (JEV) accounts for ~ 5-20% of AES cases, but ~75% of AES cases are of unknown etiology. We identified a gemykibivirus in CSF collected in 2020 from a male child with AES using metagenomic next-generation sequencing. Gemykibiviruses are single stranded, circular DNA viruses in the family

Indexed as

acute encephalitis syndromeemerging infectionGemykibivirusmetagenomic analysis

Identifiers

PMID38405898
PMCPMC10889008

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.