Evidence map›Paper›PMID 38405859›Full record

ArticlebioRxiv : the preprint server for biology2024

Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer.

Alessia Catozzi, Maria Peiris-Pagès, Sam Humphrey, Mitchell Revill, Derrick Morgan, Jordan Roebuck, Yitao Chen, Bethan Davies-Williams, Alice Lallo, Melanie Galvin and 12 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 3 countries.

Alessia CatozziCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Maria Peiris-PagèsCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Sam HumphreyCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Mitchell RevillCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Derrick MorganCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Jordan RoebuckCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Yitao ChenCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Bethan Davies-WilliamsCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Alice LalloCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Melanie GalvinCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Simon P PearceCancer Research UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.
Alastair KerrCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Lynsey PriestCancer Research UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.
Victoria FoyCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Mathew CarterCancer Research UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.
Rebecca CaeserDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Joseph ChanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Charles M RudinDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Fiona BlackhallCancer Research UK Lung Cancer Centre of Excellence, Manchester, United Kingdom.
Kristopher K FreseCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Caroline DiveCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Kathryn L SimpsonCancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
Cancer Research UK · GBMemorial Sloan Kettering Cancer Center · USUniversity of Manchester · GB

Funding

Coordinating center for the NCI small cell lung cancer research consortiumU24CA213274 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Lauren Averett Byers, JOHN D. MINNA · 2017 to 2026
$12.9M
Novel therapeutic development for small cell lung cancerR35CA263816 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Charles M. Rudin · 2021 to 2026
$6.3M
Cancer Research UK 29569Cancer Research UK CTRNBC-2022/100001NCI NIH HHS R35 CA263816NCI NIH HHS U24 CA213274
6 · The paper itself

Abstract

Molecular subtypes of Small Cell Lung Cancer (SCLC) have been described based on differential expression of transcription factors (TFs)

Identifiers

PMID38405859
PMCPMC10888785
OpenAlexW4391913843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.