Evidence map›Paper›PMID 38405845›Full record

ArticlebioRxiv : the preprint server for biology2024

NEKL-4 regulates microtubule stability and mitochondrial health in

Kaiden M Power, Ken C Nguyen, Andriele Silva, Shaneen Singh, David H Hall, Christopher Rongo, Maureen M Barr

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kaiden M PowerDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, United States of America.
Ken C NguyenCenter for C. elegans Anatomy, Albert Einstein College of Medicine, Bronx, NY, United States of America.
Andriele SilvaDepartment of Biology, Brooklyn College of the City University of New York, Brooklyn, NY, United States of America.
Shaneen SinghDepartment of Biology, Brooklyn College of the City University of New York, Brooklyn, NY, United States of America.
David H HallCenter for C. elegans Anatomy, Albert Einstein College of Medicine, Bronx, NY, United States of America.
Christopher RongoWaksman Institute of Microbiology, Rutgers University, Piscataway, NJ, United States of America.
Maureen M BarrDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, United States of America.ORCID 0000-0003-4483-2952
Rutgers, The State University of New Jersey · USAlbert Einstein College of Medicine · USCity University of New York · US

Funding

WormBase: a core data resource for C. elegans and other nematodesU41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KERSEY, PAUL, SCHEDL, TIM · 2013 to 2017
$20.5M
Polycystins, cilia, and extracellular vesicles in C. elegansR01DK059418 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Maureen M Barr · 2001 to 2026
$9.9M
Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Genetics Analysis of Neuronal Hypoxic Stress ResistanceR01GM101972 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI RONGO, CHRISTOPHER G · 2012 to 2024
$4.1M
Nephronophthisis-related ciliopathies and ciliary specializationR01DK116606 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2018 to 2026
$3.7M
Fundamental biology of neuronal extracellular vesicles - RenewalRF1NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2021 to 2026
$3.0M
Fundamental Biology of Neuronal Extracellular VesiclesR01NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI BARR, MAUREEN M · 2024 to 2025
$785k
Role of a NIMA-related kinase in neuronal microtubule stability and transportF31NS122438 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI POWER, KAIDEN MICHAEL · 2022 to 2023
$74k
NHGRI NIH HHS U41 HG002223NIDDK NIH HHS R01 DK059418NIDDK NIH HHS R01 DK116606NIGMS NIH HHS R01 GM101972NIH HHS P40 OD010440NIH HHS R24 OD010943NINDS NIH HHS F31 NS122438NINDS NIH HHS R01 NS120745NINDS NIH HHS RF1 NS120745
6 · The paper itself

Abstract

Ciliopathies are often caused by defects in the ciliary microtubule core. Glutamylation is abundant in cilia, and its dysregulation may contribute to ciliopathies and neurodegeneration. Mutation of the deglutamylase CCP1 causes infantile-onset neurodegeneration. In

Identifiers

PMID38405845
PMCPMC10888866
OpenAlexW4391807680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.