Evidence map›Paper›PMID 38405840›Full record

ArticlebioRxiv : the preprint server for biology2024

Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes.

Denise M Drotar, Ana Karen Mojica-Avila, Drew T Bloss, Christian M Cohrs, Cameron T Manson, Amanda L Posgai, MacKenzie D Williams, Maigan A Brusko, Edward A Phelps, Clive H Wasserfall and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Denise M DrotarDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Ana Karen Mojica-AvilaInstitute of Physiology, Faculty of Medicine, Technische Universität Dresden, Germany.
Drew T BlossDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Christian M CohrsInstitute of Physiology, Faculty of Medicine, Technische Universität Dresden, Germany.
Cameron T MansonDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Amanda L PosgaiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.ORCID 0000-0002-9491-0958
MacKenzie D WilliamsDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Maigan A BruskoDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Edward A PhelpsJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL USA.
Clive H WasserfallDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
Stephan SpeierInstitute of Physiology, Faculty of Medicine, Technische Universität Dresden, Germany.
Mark A AtkinsonDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, 32610, USA.
University of Florida · USHelmholtz Zentrum München · DE

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
Co-registration of Cell Organization, Phenotype and Function in the Human Pancreas During Type 1 DiabetesR01DK131059 · NIDDK · UNIVERSITY OF FLORIDA · PI ATKINSON, MARK A. · 2021 to 2025
$2.5M
Regional and lobular heterogeneity of human pancreas morphology and function in type 1 diabetes pathogenesisR01DK123292 · NIDDK · UNIVERSITY OF FLORIDA · PI ATKINSON, MARK A., SPEIER, STEPHAN · 2020 to 2023
$1.7M
NIAID NIH HHS P01 AI042288NIDDK NIH HHS R01 DK123292NIDDK NIH HHS R01 DK131059
6 · The paper itself

Abstract

Histopathological heterogeneity in human pancreas has been well documented; however, functional evidence at the tissue level is scarce. Herein we investigated

Identifiers

PMID38405840
PMCPMC10888906
OpenAlexW4391743843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.