Evidence map›Paper›PMID 38405799›Full record

ArticlebioRxiv : the preprint server for biology2024

A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to

Abubakar Muhammad, Zsuzsa Sarkadi, Thomas van Emden, Agnisrota Mazumder, Matias Capella, Gergely Fekete, Vishnu N Suma Sreechakram, Bassem Al-Sady, Balázs Papp, Ramón Ramos Barrales and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Abubakar MuhammadInstitute for Genetics, Justus-Liebig-University Giessen, Giessen, Germany.ORCID 0000-0002-8169-2701
Zsuzsa SarkadiBioMedical Center (BMC), Division of Physiological Chemistry, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany.ORCID 0000-0002-9432-7631
Thomas van EmdenBioMedical Center (BMC), Division of Physiological Chemistry, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany.ORCID 0000-0001-7389-3741
Agnisrota MazumderInstitute for Genetics, Justus-Liebig-University Giessen, Giessen, Germany.ORCID 0009-0000-1988-8650
Matias CapellaBioMedical Center (BMC), Division of Physiological Chemistry, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany.ORCID 0000-0003-4804-243X
Gergely FeketeSynthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.ORCID 0000-0001-9939-4860
Vishnu N Suma SreechakramInstitute for Genetics, Justus-Liebig-University Giessen, Giessen, Germany.ORCID 0000-0002-7341-3354
Bassem Al-SadyDepartment of Microbiology & Immunology, George Williams Hooper Foundation, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-8996-7941
Balázs PappSynthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.ORCID 0000-0003-3093-8852
Ramón Ramos BarralesBioMedical Center (BMC), Division of Physiological Chemistry, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany.ORCID 0000-0002-5256-3222
Sigurd BraunInstitute for Genetics, Justus-Liebig-University Giessen, Giessen, Germany.ORCID 0000-0001-6399-8574
Justus-Liebig-Universität Gießen · DEHUN-REN Szegedi Biológiai Kutatóközpont · HUConsejo Superior de Investigaciones Científicas · ESMax Planck Institute of Biochemistry · DEUniversidad Nacional del Litoral · ARUniversity of California, San Francisco · US

Funding

Tracking how molecular machines propagate epigenetic information in time and spaceR35GM141888 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AL-SADY, BASSEM · 2021 to 2025
$2.3M
NIGMS NIH HHS R35 GM141888
6 · The paper itself

Abstract

Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components have been linked to heterochromatin establishment, a comprehensive view of the underlying pathways at diverse heterochromatin domains remains elusive. Here, we developed a systematic approach to identify factors involved in heterochromatin silencing at pericentromeres, subtelomeres, and the silent mating type locus in

Indexed as

gene silencinggenetic reporter screensHeterochromatin maintenancemetabolismreplication

Identifiers

PMID38405799
PMCPMC10888830
OpenAlexW4391846193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.