Evidence map›Paper›PMID 38405750›Full record

ArticlebioRxiv : the preprint server for biology2024

Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid- and IL4-Driven Macrophage Programming.

Dinesh K Deochand, Marija Dacic, Michael J Bale, Andrew W Daman, Steven Z Josefowicz, David Oliver, Yurii Chinenov, Inez Rogatsky

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dinesh K DeochandHospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.ORCID 0000-0002-7395-9250
Marija DacicHospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.
Michael J BaleDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Andrew W DamanDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0001-8144-0574
Steven Z JosefowiczDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0001-7453-779X
David OliverHospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.
Yurii ChinenovHospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.ORCID 0000-0001-5226-8541
Inez RogatskyHospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.ORCID 0000-0003-3514-5077
Hospital for Special Surgery · USCornell University · US

Funding

Glucocorticoid-regulated transcription networks in macrophage biologyR01DK099087 · NIDDK · HOSPITAL FOR SPECIAL SURGERY · PI INEZ ROGATSKY · 2014 to 2026
$6.0M
Histone Variant H3.3 as a Transcription Rheostat in the Immune SystemR01AI148416 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Steven Zvi Josefowicz · 2020 to 2026
$4.6M
Post-Initiation control of transcription in inflammatory macrophagesR01AI148129 · NIAID · HOSPITAL FOR SPECIAL SURGERY · PI ROGATSKY, INEZ · 2020 to 2024
$3.0M
Describing the Epigenetic Mechanisms in Control of Hematopoietic Development and Rapid Inflammatory ResponsesF31HL152706 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI DAMAN, ANDREW · 2021 to 2023
$140k
NHLBI NIH HHS F31 HL152706NIAID NIH HHS R01 AI148129NIAID NIH HHS R01 AI148416NIDDK NIH HHS R01 DK099087
6 · The paper itself

Abstract

Macrophages adopt distinct phenotypes in response to environmental cues, with type-2 cytokine interleukin-4 promoting a tissue-repair homeostatic state (M2

Indexed as

chromatin and epigenomicsenhancer landscapeglucocorticoid receptorHomeostatic macrophage programmingkruppel-like factor 4tissue repair and inflammationtranscriptional regulation

Identifiers

PMID38405750
PMCPMC10888924
OpenAlexW4391921592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.