Evidence map›Paper›PMID 38405745›Full record

ArticlebioRxiv : the preprint server for biology2024

NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT.

Vinay Shukla, Ayelen Moreno-Irusta, Kaela M Varberg, Marija Kuna, Khursheed Iqbal, Anna M Galligos, John D Aplin, Ruhul H Choudhury, Hiroaki Okae, Takahiro Arima and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Vinay ShuklaInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0002-6181-269X
Ayelen Moreno-IrustaInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0001-6810-6475
Kaela M VarbergInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0001-9672-4158
Marija KunaInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0002-5367-731X
Khursheed IqbalInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0002-6742-4591
Anna M GalligosInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.
John D AplinMaternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, The University of Manchester, Manchester M13 9WL, United Kingdom.ORCID 0000-0001-8777-9261
Ruhul H ChoudhuryMaternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, The University of Manchester, Manchester M13 9WL, United Kingdom.
Hiroaki OkaeDepartment of Trophoblast Research, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811 Japan.
Takahiro ArimaDepartment of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Michael J SoaresInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID 0000-0001-7158-1592
University of Kansas Medical Center · USUniversity of Manchester · GBKumamoto University · JPTohoku University · JP

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
TROPHOBLAST DIFFERENTIATIONR01HD020676 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MICHAEL J SOARES · 1986 to 2026
$10.1M
Stem Cells and Epigenetics of Trophoblast Lineage DevelopmentP01HD079363 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2014 to 2018
$5.7M
Anti-Coagulation Factors and PlacentationR01HD099638 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2019 to 2023
$2.5M
Trophoblast-Guided Uterine Transformation in the Establishment of PregnancyR01HD105734 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MICHAEL J SOARES · 2022 to 2026
$2.2M
Regulation of Invasive Trophoblast Cell Lineage DevelopmentR00HD107262 · NICHD · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI VARBERG, KAELA MARGARET · 2023 to 2025
$740k
Supplement (Covid) to Regulation of endovascular trophoblast cell development and uterine spiral artery remodelingF32HD096809 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI VARBERG, KAELA MARGARET · 2018 to 2021
$232k
Regulation of Invasive Trophoblast Cell Lineage DevelopmentK99HD107262 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI VARBERG, KAELA MARGARET · 2022 to 2023
$142k
NICHD NIH HHS F32 HD096809NICHD NIH HHS K99 HD107262NICHD NIH HHS P01 HD079363NICHD NIH HHS R00 HD107262NICHD NIH HHS R01 HD020676NICHD NIH HHS R01 HD099638NICHD NIH HHS R01 HD105734NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

Trophoblast stem (

Indexed as

extravillous trophoblast cellsNOTUMPlacentaWNT

Identifiers

PMID38405745
PMCPMC10888853
OpenAlexW4391823920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.