ArticleNature water2023
Substantial defluorination of polychlorofluorocarboxylic acids triggered by anaerobic microbial hydrolytic dechlorination.
Article in Nature water, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Biotransformation and biodefluorination of chlorinated polyfluorocarboxylic acids bybioRxiv : the preprint server for biology · 2026Article
- From carboxylates to chlorinated sulfonates: Contrasting fate and treatment prospects of GenX and F53B in WWTPs.The Science of the total environment · 2025Review
- Recent advances in microbial and bioelectrochemical strategies for degradation of per- and polyfluoroalkyl substances: mechanisms, limitations, and research opportunities.Biotechnology letters · 2025Review
- Sustainable bioactive hydrogels for organic contaminant elimination in wastewater.Nature communications · 2025Article
- Broad-spectrum capture of hundreds of per- and polyfluoroalkyl substances from fluorochemical wastewater.Nature communications · 2025Article
- Emerging Per- and Polyfluoroalkyl Substances in Tap Water from the American Healthy Homes Survey II.Environmental science & technology · 2025Article
- Pyrolysis of Two Perfluoroalkanesulfonates (PFSAs) and PFSA-Laden Granular Activated Carbon (GAC): Decomposition Mechanisms and the Role of GAC.Environmental science & technology · 2024Article
- Speciation and biogeochemical behavior of perfluoroalkyl acids in soils and their environmental implications: A review.Eco-Environment & Health · 2024Review
- Legacy and Novel Per- and Polyfluoroalkyl Substances in Surface Soils across China: Source Tracking and Main Drivers for the Spatial Variation.Environmental science & technology · 2024Article
- Burning question: Rethinking organohalide degradation strategy for bioremediation applications.Microbial biotechnology · 2024Review
- Electron bifurcation and fluoride efflux systems implicated in defluorination of perfluorinated unsaturated carboxylic acids byScience advances · 2024Article
- Aerobic Biotransformation and Defluorination of Fluoroalkylether Substances (ether PFAS): Substrate Specificity, Pathways, and Applications.Environmental science & technology letters · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Chlorinated polyfluorocarboxylic acids (Cl-PFCAs) derived from the widely used chlorotrifluoroethylene (CTFE) polymers and oligomers may enter and influence the aquatic environment. Here, we report significant defluorination of Cl-PFCAs by an anaerobic microbial community via novel pathways triggered by anaerobic microbial dechlorination. Cl-PFCAs first underwent microbial reductive, hydrolytic, and eliminative dechlorination, and it was the hydrolytic dechlorination that led to significant spontaneous defluorination. Hydrolytic dechlorination was favored with increased Cl-substitutions. An isolated, highly enriched anaerobic defluorinating culture was dominated by two genomes closest to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.