Evidence map›Paper›PMID 38405263›Full record

ArticleAnnals of 3D printed medicine2024

Utility of a Low-Cost 3-D Printed Microscope for Evaluating Esophageal Biopsies.

Daniel G Rosen, Evandro Sobroza de Mello, Sadhna Dhingra, Sanford M Dawsey, Joe Knapper, Richard Bowman, Sharmila Anandasabapathy

Open access · goldAbstract read
In one paragraph

Article in Annals of 3D printed medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Daniel G RosenDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Tx.
Evandro Sobroza de MelloDepartment of Pathology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
Sadhna DhingraDepartment of Pathology, Houston Methodist Hospital, Houston, Tx.
Sanford M DawseyNutritional Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, Maryland, United States of America.
Joe KnapperSchool of Physics and Astronomy, University of Glasgow, UK.
Richard BowmanSchool of Physics and Astronomy, University of Glasgow, UK.
Sharmila AnandasabapathySection of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas.
University of Glasgow · GBBaylor College of Medicine · USMethodist Hospital · USMichael E. DeBakey VA Medical Center · USNational Cancer Institute · USUniversidade de São Paulo · BR

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
High Resolution Microendoscopy for the Management of Esophageal NeoplasiaR01CA181275 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Sharmila Anandasabapathy, Amy L McGuire · 2014 to 2026
$6.3M
NCI NIH HHS R01 CA181275
6 · The paper itself

Abstract

In this manuscript we assessed the utility of a low-cost 3D printed microscope to evaluate esophageal biopsies. We conducted a comparative analysis between the traditional microscope and our 3-D printed microscope, utilizing a set of esophageal biopsy samples obtained from patients undergoing screening endoscopy. Two pathologists independently examined 30 esophageal biopsies by light microscopy and digital images obtained using a low-cost 3D printed microscope (Observer 1 and 2). The glass slide consensus diagnosis was compared to the findings of 2 additional pathologist who independently just reviewed the digital images (Observer 3 and 4). The intra-observer agreement was substantial to almost perfect for observer 1 (k:0.64) and 2 (k:0.84). All four observers had 100% sensitivity and negative predictive value, whereas specificity ranged from 59% to 100% and positive predictive value ranged from 21% to 100%. The PPV and specificity were lower for the two Observers (3 and 4) who just examined the digital images. Overall, our results suggest that telepathology may be used with high sensitivity and specificity, utilizing the pictures produced by our 3D-printed microscope.

Indexed as

3d-printerlow-costtelepathology

Identifiers

PMID38405263
PMCPMC10887376
OpenAlexW4390898769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.