Evidence map›Paper›PMID 38405142›Full record

ArticleFrontiers in endocrinology2024

Association between red cell distribution width-and-albumin ratio and the risk of peripheral artery disease in patients with diabetes.

Dongling Li, Juan Long, Jialu Zhang, Meinan He, Qingxiang Zeng, Qiaoling He, Wanhua Zhan, Yongqian Chi, Mengchen Zou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dongling LiDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Juan LongDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jialu ZhangDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Meinan HeDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qingxiang ZengDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qiaoling HeDepartment of Endocrinology, Central Hospital of Zengcheng District, Guangzhou, China.
Wanhua ZhanDepartment of Endocrinology, Central Hospital of Zengcheng District, Guangzhou, China.
Yongqian ChiDepartment of Endocrinology, Central Hospital of Zengcheng District, Guangzhou, China.
Mengchen ZouDepartment of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Southern Medical University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The aim of this study is to explore the association between red blood cell distribution width-to-albumin ratio (RAR) and the risk of peripheral artery disease (PAD) in patients with diabetes. Methods: This cross-sectional study extracted the data of 1,125 participants with diabetes from the National Health and Nutrition Examination Survey database. A weighted univariable logistic regression model was used to explore variables associated with PAD. With PAD as the outcome variable, a weighted logistic regression model was established. The odds ratio (OR) and 95% confidence interval (CI) were effect size. Results: After adjusting for covariates, the risk of PAD in patients with diabetes was observed in those with higher RAR (OR = 1.83; 95% CI: 1.06-3.15). In addition, RAR ≥3.25 was related to increased risk of PAD in patients with diabetes (OR = 2.04; 95% CI: 1.05-3.95). In people with diabetes aged ≥65, RAR was a risk factor for PAD with an OR value of 2.67 (95% CI: 1.30-5.46). RAR ≥3.25 was associated with increased risk of PAD (OR = 3.06; 95% CI: 1.15-8.11) relative to RAR <2.80. In people with diabetes who smoked, the risk of PAD was elevated in those with RAR ≥3.25 (OR = 2.85; 95% CI: 1.28-6.32). As for patients with cardiovascular disease, the risk of PAD was elevated as the increase of RAR (OR = 2.31; 95% CI: 1.05-5.10). RAR ≥3.25 was correlated with increased risk of PAD (OR = 3.75; 95% CI: 1.42-9.87). The area under the curve of RAR for the risk of PAD in patients with diabetes was 0.631 (95% CI: 0.588-0.675). Conclusion: A higher RAR was related to increased risk of PAD in patients with diabetes. The findings might offer a reference for the management of PAD in patients with diabetes.

Indexed as

Diabetes MellitusPeripheral Arterial DiseaseAlbuminsCross-Sectional StudiesErythrocyte IndicesHumansNutrition SurveysAlbuminsassociationdiabetesperipheral artery diseaseRDW (red cell distribution width)red cell distribution width and albumin ratio

Identifiers

PMID38405142
PMCPMC10884210
OpenAlexW4391690886

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.