Evidence map›Paper›PMID 38404646›Full record

ArticleIntensive care medicine. Paediatric and neonatal2024

Safety of primary nasotracheal intubation in the pediatric intensive care unit (PICU).

Laurence Ducharme-Crevier, Jamie Furlong-Dillard, Philipp Jung, Fabrizio Chiusolo, Matthew P Malone, Shashikanth Ambati, Simon J Parsons, Conrad Krawiec, Awni Al-Subu, Lee A Polikoff and 22 more

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In one paragraph

Article in Intensive care medicine. Paediatric and neonatal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 6 countries.

Laurence Ducharme-CrevierPediatric Intensive Care Unit, Department of Pediatrics, CHU Sainte-Justine Université de Montréal, Montréal, QC H3T 1C5 Canada.ORCID 0000-0003-0187-9136
Jamie Furlong-DillardDepartment of Pediatric Critical Care, Norton Children's Hospital, University of Louisville, Louisville, KY USA.
Philipp JungDepartment of Pediatrics, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany.
Fabrizio ChiusoloDepartment of Anesthesia and Critical Care, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Matthew P MaloneDivision of Critical Care Medicine, Department of Pediatrics, The University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR USA.
Shashikanth AmbatiDivision of Pediatric Critical Care, Department of Pediatrics, Albany Medical Center, Albany, NY USA.
Simon J ParsonsSection of Critical Care Medicine, Department of Pediatrics, Alberta Children's Hospital, Calgary, AB Canada.
Conrad KrawiecPediatric Critical Care, Department of Pediatrics, College of Medicine, Penn State Health Children's Hospital, Hershey, PA USA.
Awni Al-SubuDepartment of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI USA.
Lee A PolikoffDivision of Pediatric Critical Care Medicine, Warren Alpert Medical School of Brown University, Providence, RI USA.
Natalie NapolitanoRespiratory Therapy Department, Children's Hospital of Philadelphia, Philadelphia, PA USA.
Keiko M TarquinioCollege of Health Professions, the Medical University of South Carolina, Charleston, SC USA.
Asha ShenoiDivision of Pediatric Critical Care, Department of Pediatrics, University of Kentucky School of Medicine, Lexington, KY USA.
Andrea TalukdarPediatric Critical Care, Medical Center/Children's Hospital and Medical Center of Omaha, University of Nebraska, Omaha, NE USA.
Palen P MalloryDivision of Pediatric Critical Care Medicine, Duke University, Durham, NC USA.
John S GiulianoDepartment of Pediatrics (Critical Care Medicine), Yale University School of Medicine, New Haven, CT USA.
Ryan K BreuerDivision of Critical Care Medicine, Department of Pediatrics, Oishei Children's Hospital, Buffalo, NY USA.
Krista KierysPediatric Intensive Care Unit, Penn State Health, Philadelphia, PA USA.
Serena P KellyDivision of Pediatric Critical Care, OHSU Doernbecher Children's Hospital, Portland, OR USA.
Makoto MotomuraDivision of Pediatric Critical Care Medicine, Aichi Children's Health and Medical Center, Obu, Aichi Japan.
Ron C SandersSection of Critical Care, Department of Pediatrics, UAMS/Arkansas Children's Hospital, Little Rock, AR USA.
Ashley FreemanPediatric Critical Care, Department of Pediatrics, Children's Hospital of Georgia at the Medical College of Georgia, Augusta, GA USA.
Yuki NagaiDivision of Pediatric Critical Care Medicine, Kobe Children's Hospital, Kobe, Hyogo Japan.
Lily B Glater-WeltPediatric Critical Care Medicine, Cohen Children's Medical Center of New York/Northwell, Queens, NY USA.
Joseph WilsonPediatric Critical Care Medicine, University of Louisville, Louisville, KY USA.
Mervin LoiDepartment of Pediatric Subspecialties, Children's Intensive Care Unit KK Women's and Children's Hospital, Singapore, Singapore.
Michelle Adu-DarkoDivision of Pediatric Critical Care, Department of Pediatrics, University of Virginia Hospital, Charlottesville, VA USA.
Justine ShultsDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.
Vinay NadkarniDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA USA.
Guillaume EmeriaudPediatric Intensive Care Unit, Department of Pediatrics, CHU Sainte-Justine Université de Montréal, Montréal, QC H3T 1C5 Canada.
Akira NishisakiDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA USA.
National Emergency Airway Registry for Children (NEAR4KIDS), Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network
Children's Hospital of Philadelphia · USArkansas Children's Hospital · USCentre Hospitalier Universitaire Sainte-Justine · CAUniversity of Louisville · USAichi Medical University · JPAlbany Medical Center Hospital · USAlberta Children's Hospital · CAAugusta University · USBambino Gesù Children's Hospital · ITBrown University · USChildren's Hospital & Medical Center · USCohen Children's Medical Center · USDoernbecher Children's Hospital · USDuke University · USKK Women's and Children's Hospital · SGKobe Children's Hospital · JPMedical University of South Carolina · USPenn State Milton S. Hershey Medical Center · USPennsylvania State University · USUniversity Hospital Schleswig-Holstein · DE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
AHRQ HHS R18 HS024511NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Background: Nasal tracheal intubation (TI) represents a minority of all TI in the pediatric intensive care unit (PICU). The risks and benefits of nasal TI are not well quantified. As such, safety and descriptive data regarding this practice are warranted. Methods: We evaluated the association between TI route and safety outcomes in a prospectively collected quality improvement database (National Emergency Airway Registry for Children: NEAR4KIDS) from 2013 to 2020. The primary outcome was severe desaturation (SpO Results: A total of 22,741 TIs [nasal 870 (3.8%), oral 21,871 (96.2%)] were reported from 60 PICUs. Infants were represented in higher proportion in the nasal TI than the oral TI (75.9%, vs 46.2%), as well as children with cardiac conditions (46.9% vs. 14.4%), both Conclusion: In this large international prospective cohort study, the risk of severe peri-intubation complications was not significantly higher. Nasal TI is used in a minority of TI in PICUs, with substantial differences in patient, provider, and practice compared to oral TI.A prospective multicenter trial may be warranted to address the potential selection bias and to confirm the safety of nasal TI.

Indexed as

Adverse eventsEndotracheal intubationNasal intubationPediatric intensive care

Identifiers

PMID38404646
PMCPMC10891187
OpenAlexW4392098475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.